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三波长分光光度法测定18-氨基酸注射液中色氨酸和酪氨酸的含量 被引量:2

Determination of tryptophane and tyrosine contents in 18-amino acid injection with three-wavelength spectrophotometry
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摘要 目的:研究不经分离直接测定18-氨基酸注射液中色氨酸和酪氨酸的含量。方法:运用三波长分光光度法测定色氨酸和酪氨酸的含量。结果:三波长分光光度法简便,重现性好。结论:本方法可作为该制剂半成品及成品的质量控制。 :OBJECTIVE To directly determine the contents of tryptophane and tyrosine in 18-amino ac id injection without separation. METHODS The tyrptophane and tyrosine contents were determined with three -wavelength spectrophotometry. RESULTS The average recovery rate of tryptophane was 99.99%,RS D=0.32%,and the average rcovery rate of tyrosine was 100.1%,RSD= 0.62%.CONCLUSIONS This method is simple and repeatable, and can be used as the quality contro l method for the finished products or semi-finished products of this preparatio n.
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2001年第9期534-535,共2页 Chinese Journal of Hospital Pharmacy
关键词 三波长分光光度法 色氨酸 酪氨酸 18-氨基酸注射液 含量 : three-wavelength spectrophotometry determination tryptophane tyrosine
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