摘要
目的 :观察剖宫产术后经静脉自控镇痛 (PCIA)与硬膜外自控镇痛 (PCEA)的镇痛效果及对血浆催乳素含量的影响。方法 :选择 36例择期行剖宫产术产妇 ,随机分为PCIA组 (n =12 )、PCEA组 (n =12 )和对照组 (n =12 )。镇痛药应用芬太尼 ,PCIA组持续剂量 15～ 2 0 μg/h ,PCEA组持续剂量 8～ 9μg/h ,PCEA组镇痛液中含 1 2 5g/L的布比卡因 ,镇痛时间均为 48h ,对照组不用止痛液。采用VAS评分比较两组镇痛效果 ;放射免疫法 (RIA)测血浆催乳素 (PRL)含量。结果 :两组镇痛后各时点VAS评分无差异 (P >0 .0 5 ) ;PCEA组术后 2 4h ,48h血浆PRL含量显著高于PCIA组和对照组 (P <0 .0 5 ) ;初乳时间PCEA组早于PCIA组 ,PCIA组早于对照组 (P <0 .0 5 )。结论 :两种镇痛方法均安全确切 。
Aim:To observe the effects of postoperative analgesia by PCIA and PCEA and change of plasma prolactin(PRL) content after cesarean section.Methods: A total of 36 pregnant women undergoing cesarean section were randomly divided into PCIA group ( n=12), PCEA group( n=12 ) and control group( n=12) .The dosage of fentanyl in PCIA group and PCEA group was 15～20 μg/h and 8～9 μg/h respectively,the analgesia solution in PCEA group contained 1.25 g/L bupivacaine.The analgesia time of the 2 groups were both 48 h ,and there was no analgesia solution in control group.The analgesia effects of the 2 groups were evaluated by VAS method and the content of PRL was measured by RIA.Results :There was no significant difference between the 2 groups in VAS after analgesia( P>0.05) ,the content of PRL in PCEA group was significantly higher than those in PCIA group and control group at 24 h and 48 h after operation( P<0.05 ),the colostrum time of PCEA group was earlier than that of PCIA group,and the colostrum time of PCIA group was earlier than that of control group( P<0.05 ).Conclusion: Two analgesia methods are both safe and effective and the colostrum time of PCEA group is moved up.
出处
《河南医科大学学报》
北大核心
2001年第5期579-580,共2页
Journal of Henan Medical University
