摘要
目的 观察血清Ⅳ型胶原含量在健康人群、急性肝炎、慢性肝炎及肝纤维患者中的变化 ,评价Ⅳ型胶原对肝纤维化的诊断价值。方法 采用放射免疫法测定血清Ⅳ型胶原含量。结果 慢性肝炎及肝纤维化患者血清Ⅳ型胶原含量增高。与正常对照组比较 ,差异有显著性 (P <0 .0 5 )。结论 Ⅳ胶原是判断肝纤维化程度的较好指标。联合测定慢性肝炎。
Objective To study the diagnostic value of type Ⅳ collagen in hepatic fibrosis.Methods Serum level of type Ⅳ collagen was measured by means of radioimmunoassay.. Serum levels of 36 cases of acute hepatitis, 26 chronic hepatitis, 25 hepatic fibrosis and 30 normal control were measured for comparison and analyzed. Results As compared with normal controls, serum levels of type Ⅳ collagen were statistically higher in patients with chronic hepatitis and hepa tofibrosis ( P< 0.05).Conclusion Serum type Ⅳ collagen may be a preferable index for diagnosing hepatofibrosis and also in patients with chronic hepatitis.
出处
《同济大学学报（医学版）》
CAS
2001年第4期47-48,共2页
Journal of Tongji University(Medical Science)
关键词
Ⅳ胶原
肝纤维化
放射免疫检测
type Ⅳ collagen
liver fibrosis
radioimmunodetection
