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一种新的肿瘤相关耐药蛋白——乳腺癌耐药蛋白 被引量:2

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摘要 乳腺癌耐药蛋白(BCRP)是1998年才发现的一种与多药耐药(MDR)相关的肿瘤耐药蛋白,它与P-gp和多药耐药相关蛋白(MRP)同属ABC转运蛋白超家族成员。本文就BCRP近两年的研究情况作一综述。
作者 罗云
出处 《国外医学(输血及血液学分册)》 2001年第4期287-289,共3页 Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
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参考文献10

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同被引文献8

  • 1Hamada H, Tsuruo T. Purification of the 170 to 180-kilodal ton membrane glycoprotein associated with multidrug resist ance. 170 to 180-kilodalton membrane glycoprotein is an ATPase[J]. J Biol Chem, 1988,263(1): 1454- 1458.
  • 2Lautier D, Canitrot Y, Deeley RG, et al. Multidrug resist ance mediated by the multidrug resistance protein (MRP)gene[J]. Biochem Pharmacol, 1996, 52(7) :967-977.
  • 3Sharp SY,Smith V, Hobbs S, et al. Lack of a role for MRP1 in platinum drug resistance in human ovarian cancer cell lines[J]. Br J Cancer, 1998,78(2) : 175-180.
  • 4Kool Mde,Hass M,Scheffer GL,et al. Analysis of expression of cMOAT ( MRP2 ), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene(MRP1), in human cancer cell lines[J]. Cancer Res, 1997,57(8): 3537-3547.
  • 5Dingemans AM, Van Ark-Otte J. Van der Valk P. Expression of human vault protein LRP in human lung cancer samples and normal lung tissue[J]. Ann Oncol, 1996,7(8): 625-630.
  • 6Van den Heuvel-Eibrink MM, Sconneveld P, Pieters R. The prognostic significance of membrance transport-associated multidrug resistance (MDR) proteins in leukemia[J]. Int J Clin Pharmacol Ther,2000,38(3) :94-110.
  • 7王恒毅,陈孝平.耐药蛋白差异性表达与肿瘤个体化化学治疗关系的研究进展[J].中国现代普通外科进展,2008,11(4):336-338. 被引量:4
  • 8肖镇,黄彬涛,崔鹤,高大.白血病患者耐药蛋白表达与预后相关性[J].肿瘤学杂志,2008,14(9):755-757. 被引量:1

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