摘要
目的 :了解沈阳地区唇腭裂发病现况及年度和城乡分布的特点。方法 :对沈阳地区 14所医院自 1993年 3月至1998年 6月间的出生缺陷资料进行整理及唇腭裂发病现况进行分析。结果 :在沈阳地区 812 0 2名新生儿中发现唇腭裂患儿14 7例 ,发病率为 1 81‰。各种类型唇腭裂发病率依次为 :唇裂合并腭裂 :1 16‰ ,唇裂 :0 4 7‰ ,腭裂 :0 18‰ ,且彼此间差异有统计学意义 ;进一步对各年度、城乡发病率进行研究发现 :年度平均发病率为 1 81‰ ;城乡间发病率有显著差异 (x2 =5 13 5 ,p<0 0 5 )。 14 7例唇腭裂中伴有其它系统畸形 2 1例。结论 :提示环境因素及遗传因素对唇腭裂发病有影响。
Objective:To find out the incidence of cleft lip and cleft palate with the character of annual incidence and urban rural distribution in Shenyang.Methods:From March 1993 to June 1998,the materials of birth defect were arranged in 14 hospital in Shenyang and the incidences of cleft lip and celft palate were analysised.Results:It was found that there were 147 cases of cleft lip and cleft palate in 81202 neonates and the incidence was 1.81‰.The incidence of cleft lip with cleft palate was 1.16‰,cleft lip:0.47‰ and cleft palate:0.18‰.There were significant difference between them in statistics.Through advanced research on incidence of urban rural distribution,it was found that the average annual incidence was 1.81‰.There were also significant difference between the urban rural incidence in stastics(x 2=5.135,p<0.05).There were 21 cases concomitant with deformities of other systems in 147 cases of cleft lip and cleft palate.Conclusion:Enviromental and genetic factors may have effects on the incidence of cleft lip and cleft palate.
出处
《口腔医学》
CAS
2001年第3期157-158,共2页
Stomatology
