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急诊经皮冠状动脉腔内成形术与溶栓治疗急性心肌梗死的疗效比较 被引量:1

Comparison of direct angioplasty and thrombolysis in acute myocardial infarction.
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摘要 目的:比较急诊经皮冠状动脉腔内成形术PTCA与溶栓治疗急性心肌梗死AMI的临床疗效。方法:46例AMI患者,21例行急诊PTCA治疗,25例行溶栓治疗。结果:急诊PTCA组梗死相关血管IRA成功开通的有20例,成功率为95%;溶栓组IRA再通有17例,成功率为68%,两组比较,P<0.01。出院前左心室射血分数LVEF急诊PTCA组为0.53±0.10,溶栓组为0.54±0.16,病死率分别为5%和4%,两组间差异无显著性P>0.05。急诊PTCA组的平均费用明显比溶栓组高P<0.05。结论:急诊PTCA与溶栓治疗AMI患者,可使IRA充分有效地开通,故在条件允许的医院,可优先考虑行急诊PTCA治疗AMI。 Objective:To compare the efficacy of direct angioplasty with intravenous thrombolysis in the treatment of acute myocardial infarction (AMI). Methods:Forty six patients with AMI underwent either intravenous thrombolytic therapy (25 patients) or direct angioplasty (21 patients) were studied. Cardiac function (left ventricular ejection fraction,LVEF) was assessed during hospitalization by echocardiography. Results:The recanalizing rate of infarct related artery (IRA) was 68% in patients with thrombolytic therapy and 95% in those with direct angioplasty. There were no significant differences in age, risk factors, duration from onset of symptom and infarct location between the two groups. Conclusion: PTCA is more effective than intravenous thrombolysis in treatment of AMI since it is more likely to have successful IRA recanalization.
出处 《新医学》 北大核心 2001年第9期532-534,共3页 Journal of New Medicine
关键词 急性心肌梗死 急诊 经皮冠状动脉腔内成形术 溶栓疗法 治疗 疗效比较 Angioplasty, transluminal, percutaneous coronary Thrombolytic therapy Left ventricular ejection fractionMyocardial infarction Comparative study
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  • 1Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet, 2003, 361 (9351) : 13-20.
  • 2Nallamothu BK, Bates ER. Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything? Am J Cardiol, 2003, 92 (7) : 824-826.
  • 3Santoro GM, Valenti R, Buonamici P, et al. Relation between ST-segment changes and myocardial perfusion evaluated by myocardial contrast echocardiography in patients with acute myocardial infarction treated with direct angioplasty. Am J Cardiol, 1998, 82 (8) : 932-937.
  • 4Ross AM, Coyne KS, Reiner JS, et al. A randomized trial comparing primary angiophsty with a strategy of short-acting thrombolysis and immediate planned rescue angioplasty in acute myocardial infarction : the PACT trial J Am Coll Cardiol, 1999, 34 (7) : 1954-1962.
  • 5高润霖.急性心肌梗死诊断和治疗指南[J].中华心血管病杂志,2001,29(12):710-725. 被引量:5268

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