摘要
目的 探索一种适合于小婴儿深低温停循环灌注时的脑保护血气管理策略。方法 2 0例VSD(年龄 2～ 13个月 )婴儿按照不同血气管理和降温速度随机平均分 4组对照 ,脑功能的监测包括 :脑氧代谢参数、生化指标、脑温均匀度的比较及脑电图等。结果 快速降温期采用alpha稳态血气管理脑损害较重 ,在不同降温速度中应用 pH稳态血气管理脑损害均较轻。 结论 小婴儿深低温体外循环快速降温期应用
Objective The study explored a strategy for cerebral protection of blood gas management suitable for infants during cooling perfusion in deep hypothermia circulatory arrest. Methods According to different blood gas management methods and cooling speeds, 20 cases of VSD and severe pulmonary hypertension cases ( aged 2～13 months) were randomly divided into four groups, each containing 5 cases. Parameters for preoperative cerebral function assessment included: cerebral oxygen metabolism, biochemistry factors, brain temperature gradients, EEG. Results Brain damage was relatively severe in the rapid cooling group in which alpha stat blood gas management was used. Brain damage was relatively slight in two groups that were subjected pH stat blood gas management.Conclusions pH stat blood gas management is safe and effective in protecting the brain of young infants during rapid cooling perfusion in deep hypothermia cardiopulmonary bypass.
出处
《中华小儿外科杂志》
CSCD
北大核心
2001年第4期219-221,共3页
Chinese Journal of Pediatric Surgery
基金
卫生部科研基金资助项目 (96 2 2 88)
