摘要
用自动化图象分析仪,对大肠粘膜慢性炎症、无异型增生腺瘤、伴异型增生腺瘤和高分化管状腺癌进行形态定量分析,发现核面积均值、核面积差异度、核平均直径、核浆比率、核腺比值指数(ING)和腺体形状指数(IGF)具有最强的特征性,其中核面积和核平均直径是判断增生级别的主要因素,且呈直线密切正相关。因此作者认为,这种定量评价提供客观和可重复性的指标有助于大肠上皮异型增生的诊断和分级。
A morphometric study on the chronic inflammation, polypoidadenoma, dysplasia and well-differential double adenocarcinoma ofthe large intestine epithelium, by means of automatic image analysissystem. The results showod that the means and standard differenceof nuclear area, mean diameter, nucleus/cytoplasmic ratio, indexof nucleus-gland ratio (ING) and index of gland form (IGF) hadhad high specificity, mean area and diameter of nucleus were themajor parameteres in judging the degree of dysplasia, and they hadpositive relation. It is suggested that the quantitative evaluationshould provide objective and reproducible data useful in differentialdiagnostic of dysplasia of large intestine epithelium.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
1991年第4期273-276,共4页
Chinese Journal of Clinical and Experimental Pathology
关键词
大肠肿瘤
形态定量
异型增生
morphometry
dysplasia
large intestine epithelium
automatic image analysis
