摘要
本文对有随访结果的177例小儿特发性血小板减少性紫癜(ITP)的临床资料分析表明:小儿 ITP 可发生于任何年龄,急性 ITP(AITP)的发病高峰在1岁以内.春季发病较多.AITP 有诱因者较多,鼻衄和皮肤淤斑表现者少于慢性 ITP(CITP),而口腔粘膜及眼结膜出血则多于 CITP。颅内出血仅1例,血尿13例,便血11例.本组病例均使用泼尼松口服治疗,部分CITP 使用长春新碱,11例进行了脾切除。本组患儿随访6月～11年,最终26.8%转为 CITP,9.8%转为再发性 ITP(RITP),无1例死亡,说明小儿 ITP 预后良好.
The analysis of the clinical data in 177 children with ITP showed:The disease may occar at any age with the peak within one year. More cases were seen in spring time.Preceding infection was more frequent in AITP than in CITP.Symptomatically,epistaxes and eccymoses were more commonly seen in CITP than in AITP,while the bleeding of subcon- junctive and oral mucosa vice versa.Only one case of intracranial hemorrhage,13 cases of hematuria and 11 cases of gastrointestinal blee- ding were seen.All of them were treated first with prednison.Some of CITP received vincristine in addition and 11 cases underwent splenectomy. They were followed up from 6 months to 11 years.Ultimately,26.8% of this series turned into CITP and 9.8% into RITP.No single case died of ITP,suggesting that the prognosis of childhood ITP is fairly good.
出处
《临床血液学杂志》
CAS
1991年第4期149-152,共4页
Journal of Clinical Hematology
关键词
紫癜
血小板减少
临床
预后
儿童
Idiopathic thrombocytopenic purpura
Clinical manifestation
Prognosis
Children
