期刊文献+

Alzheimer病与糖代谢异常

原文传递
导出
摘要 葡萄糖对维护脑功能有特殊的作用。Alzheimer病存在脑局灶区性糖代谢下降 ,且与认知障碍有关 ,其机制主要是胰岛素信号转导异常 ,与非胰岛素依赖性糖尿病的病理生理过程相似。但糖尿病与Alzheimer病的关系尚无定论 ,值得进一步研究。
作者 黄流清
出处 《国外医学(神经病学.神经外科学分册)》 2001年第5期383-385,共3页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
  • 相关文献

参考文献18

  • 1Finch C, Cohen DM. Aging, metabolism, and Alzheimer disease:review and hypotheses. Exp Neurol, 1997, 143(1): 82-102.
  • 2Hoyer S. Is sporadic Alzheimer disease the brain type of non - insulin dependent diabetes? A challenging hypothesis. J Neural Transm, 1998,105(4-5): 415-422.
  • 3Kaplan R J, Greenwood CE, Winocur G. Cognitive performance is associated with glucose regulation in healthy elderly persons and can be enhanced with glucose and dietary carbohydrates. Am J Clin Nutr,2000, 72(3): 825 - 836.
  • 4Yamaji S, Ishii K, Sasaki M, et al. Evaluation of standardized uptake value to assess cerebral glucose metabolism. Clin Nucl Med, 2000, 25(1): 11-16.
  • 5Kessler J, Mielke R, Grond M, et al. Frontal lobe tasks do not reflect frontal lobe function in patients with probable Alzheimer' s disease.Int J Neurosci, 2000, 104(1-4): 1-15.
  • 6Fujimori M, Imamura T, Hirono N. Disturbances of spatial vision and object vision correlate differently with regional cerebral glucose metabolism in Alzheimer's disease. Neuropsycholngia, 2000, 38(10):1356- 1361.
  • 7Santens P, De Bleecker J, Goethals P. Differential regional cerebral uptake of (18) F - fluoro - 2 - deoxy - D - glucose in Alzheimer' s disease and frontotemporal dementia at initial diagnosis. Eur Neurol,2001, 45(1): 19-27.
  • 8Hirono N, Mori E, Ishii K. Neunnal substrates for semantic memory: a positron emission tomography study in Alzheimer' s disease. Dement Geriatr Cogn Disord, 2001, 12(1): 15-21.
  • 9Pietrini P, Furey ML, Alexander GE, et al. Association between brain functional failure and dementia severity in Alzheimer' s disease: resting versusstimulation PET study. Am J Psychiatry, 1999, 156(3): 470-473.
  • 10Higuchi M, Tashiro M, Arai H. Glucose hypometabolism and neuropatholngical correlates in brains of dementia with Lewy bodies.Exp Neurol, 2000, 162(2): 247 - 256.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部