摘要
目的 :探讨米非司酮配伍米索前列醇 (简称双米 )用于妊娠中期引产时 ,阴道后穹窿放置米索前列醇 (简称阴道米索 )的引产方法 ,并与口服米索前列醇的引产方法作对比。方法 :随机抽取 2 2 4例妊娠 13周～ 2 6周的孕妇 ,要求终止妊娠而无禁忌症者 ,运用双米引产法进行妊娠中期引产 ,米索前列醇阴道后穹窿放置者 112例 (简称放置组 ) ,口服者 112例 (简称口服组 ) ,两组进行对比分析。结果 :引产时间 :放置组最早 2小时 ,最晚 11小时 ,平均 4 .76小时 ;口服组最早 5小时 ,最晚 4 4小时 ,平均 10 .30小时 ,差异明显 (P <0 .0 5)。胃肠道反应发生率 :放置组重反应率 7% ,轻反应率 14% ,总发生率 2 1% ;口服组重反应率 75% ,轻反应率 14% ,总发生率 89% ,差异显著 (P <0 .0 1)。结论 :对于米索前列醇的使用 ,阴道后穹窿放置法其副作用相对较小 ,优于口服法 ,值得临床推广应用。
Objective: The stopping pregnancy method of putting mifepristone tables into vaginal postfornix was compared with that of take misoprostol tablets during midterm pregnancy. The different methods and effects are discussed here. Methods: 224 pregnant cases of 13 week to 26 week who demanded to stop pregnancy and were healthy enough to apply to different kind of medicine were selected randomly mifepristone tablets and misoprostol tablets method was used to stop pregnancy. The first group of 112 cases (also called the medicine-putting group) were asked to put misoprostol tablets into their vaginal postfornix; while that second group of 112 cases(also called the medicine-taking group) were asked to take misoprotol tablets. The results were analysed. Results: Stop pregnancy period, in the medicine-putting group: the shortest time is 2 hours, the longest times is 11 hours and the average is 4.76 hours. In the medicine-taking group: the shortest time is 5 hours, the longest time is 44 hours and the average is 10.30 hours. The difference was significant(P<0.05). The possibility of occurrence of serious gastrointestinal reaction, in the medicine-putting group is 7% and that of the slight one is 14%, the total possibility of occurrence is 21%. In the medicine-taking group, that of the serious one is 75%, that of the slight one is 14%, the total possibility of occurrence is 89%, the difference is significant(P<0.01). Conclusion: The medicine-putting method is significantly better that the medicine-taking method for applying misoprostol tablets.
出处
《山西中医学院学报》
2001年第1期36-37,共2页
Journal of Shanxi College of Traditional Chinese Medicine
