摘要
本文应用抗人CD_(20),CD_3及其亚群单克隆抗体,检测了43例子宫内膜异位症患者及27例正常月经周期妇女的CD_(20),CD_3,CD_4,CD_8百分率。其中24例中,重度子宫内膜异位症患者用丹参合剂保留灌肠加他莫西芬治疗,并观察了其治疗前及治疗两个疗程后CD_(20),CD_3,CD_4,CD_8,CD_4/CD_8比值的变化。结果表明:本病患者机体存在明显的免疫功能紊乱,其紊乱程度随着子宫内膜异位症的病理变化程度而上升;丹参合剂加他莫西芬治疗对调整机体免疫功能,改善子宫内膜异位症的临床症状起了良好的作用。
With endometriosis forty-three and 27 normal menstrual cycling women’s CD_(20)、CD_3、CD_4、CD_8、were measured with monoclonol antibody of antihuman CD_(20)、CD_3、and its subsets。Among those patients,24 more serious and the most serious patients were treated with Dan-shen Mixture for retention enema combinde with tamoxifen,the changes of rates of CD_(20)、CD_3、CD_4、CD_8、CD_4/CD_8 before treatment and after two courses of treatment were observed.The results showed that there were obvious disorders of immune function in the patients,thedegree of disorder rised with the degree of pathological changes of endometriosis,and treat-ment with Danshen Mixture combined with tamoxifen resulted in good actions on regulatingimmune function in the human body and improving clinical symptoms in patients with en-dometriosis.
出处
《江西医学院学报》
1994年第2期27-31,共5页
Acta Academiae Medicinae Jiangxi
关键词
子宫内膜异位
免疫学
治疗
丹参合剂
他莫西芬
雌激素拮抗剂
对比研究
endometriosis/immunology
endometriosis/therapy
Danshen Mixture
entrogen antagonists
comparative study complement word