摘要
采用放射免疫分析法（ＲＩＡ）对１５３例病毒性肝病患者进行空腹血清甘胆酸（ＳＣＧ）动态检测，并与同期血清丙氨酸转移酶（ＡＬＴ）、天门冬氨酸转移酶（ＡＳＴ）平行检测对照研究。结果表明：重型肝炎和慢性活动型肝炎ＳＣＧ水平明显高于急性肝炎和慢性迁延型肝炎（Ｐ＜０．０５）；肝病活动期ＳＣＧ水平与ＡＬＴ呈正相关（Ｐ＜０．００１）；重型肝炎、慢性活动型肝炎ＳＣＧ＞３０ｍｇ／Ｌ并持续＞４周者均预后不良。提示ＳＣＧ动态观察对肝病预后的判断具有实用价值。
The fasting serum conjugated conjugated glycocholic acid(SCG)in one hundred and rifty three pa-dents with viral liver diseases was determined dynamically by RIA method and comparedwith ALT and AST determined simultaneously. It was found that SCG level in patients withwevere hepatitis and chronic active hepatitis is much higher than that in those with acutehepatitis and chronic persistent hepatitis(P<0.05).The SCG level of liver diseases in ac-tive period is positively correlated with ALT(P <0.001).Grave prognosis is resulted in pa-tients with severe hepatitis and chronic active hepatitis,if their SCG surpasses 30 mg/L andpersists for weeks of more. It is suggested that the observation of SCG dynamic level is ofpractical value for the evaluation of the prognosis of viral liver diseases.
出处
《江西医学院学报》
1994年第1期41-44,共4页
Acta Academiae Medicinae Jiangxi
关键词
甘胆酸
病毒性肝炎
放射免疫测定
血清甘胆酸
预后
glycocholic acid/blood
glycocholic acid/diagnosis
hepatits,virous,human /diagnosis
radioimmunoassay
comparative study
