摘要
对７８例慢性阻塞性肺源性心脏病患者血小板功能进行了观察，其中缓解期４２例，急性期３６例。并与４０例正常人对照。结果表明，缓解期病人血小板粘附，血小板聚集较对照组增强（Ｐ＜０．０１）；而急性期病人血小板聚集较对照组降低、且血小板数较少，平均出血时间较延长（Ｐ＜０．０１），急性期病人经治疗后血小板聚集、血小板数有所改善。提示慢性阻塞性肺心病急性发作期血小板功能受损。
The blood platelet aggregation(Pag),platelet adhesion rate(PAd)platelet count andbleeding time were meastired in seventy eight(42 in remission period and 36 in exacerbatingperiod)patients with chronic Cor pulmonale resuIted from chronic ob5tructive pulmonarydisease (COPD)and compared with those in 40 normal subjects,It showed that tLe PAg ofblood(7.O±1.1 Ω)and PAd rate (58.63%±16.21%)in remission period were significantlyhigher thari those in the control group(P<0.01)and in exacerbating period(P<0.01),but PAg level in exacerbating period(4.0±0.9Ω)was lower than that in the control group(6.4±1.1Ω)( P<0.01).meanwhile platelet count in exacerbating period[(105±2.3)×10￣9/L]was lower then that in remissionperiod[(162±4.6)×10￣9/]and in control group[(168±5.9)×10￣9/L](P<0.01),The PAg in Cor pulmonale was related to the degree ofhypoxemia. In addition,the PAg and platelet count in exacerbating period increased signifi-cantly in 20 patients who had been treated effectively.The data indicate that the impairmentof blood PAg accompanying a fall in platelet count during exacerbating period of Cor pul-monale may lead to platelet exhaustion.
出处
《江西医学院学报》
1994年第1期33-36,共4页
Acta Academiae Medicinae Jiangxi
关键词
血小板聚集
血小板计数
肺心病
病理学
platelet aggregation
platelet count
pulmonary heart disease
compartive study
