摘要
用放射免疫方法测定山羊血浆cAMP,cGMP和cAMP/cGMP正常水平值以及感染肝片吸虫片的动态变化，结果表明：山羊表明：山羊血浆cAMP,cGMP和cAMP/cGMP的正常值分别为（0.80±0.03),(0.83±0.03)pmol.mL^-1,(0.69±0.04)，感梁1组和2组山羊在感染后第1－6周，血液中cAMP水平显著低于或低于对照组，以后两组水平相当。感染1组的cGMP水平在感染后5－9周期间低于对照组，而感染2组山的cGMP水平在感染后1－4周高于对照组。感染1组和2组山羊的cAMP/cGMP比值分别在感染后1－4周和1－6周呈现低于对照组的趋势，但差异不明显。因而，肝片吸虫感染可导致宿主的cAMP,cGMP和cAMP/cGMP紊乱。
In this paper basic levels of plasma cAMP, cGMP and cAMP / cGMP in goats and changes of them after infection with fasciola hepatica were measured by immunization radiotherapy. The result showed that the basic values of plasma cAMP, cGMP and cAMP / cGMP in goats were 0.80±0.30, 0.69±0.40 (pmol/mL).and 0.83±0.30 .The levels of plasma cAMP in infected goats in group 1 and 2 were lower than that in the control group during the 1st to the 6th weeks of postinfection. The level of cAMP in infected goats in group 1 was lower than that in the control group during the 5th to the 9th weeks of postinfection, whereas the level of cAMP in infected goats in group 2 was higher than that in the control group during the 1st to the 4th weeks of postinfection. The ratio of cAMP / cGMP in infected goats in group 1 and 2 tended to be lower than that in the control group during the 1st to the 4th weeks and during the 1st to the 6th weeks of post infection. Therefore, the infection with Fasciola hepatica can lead to the distortion of cAMP, cGMP and cAMP / cGMP.
出处
《佛山科学技术学院学报（自然科学版）》
CAS
1999年第4期33-37,共5页
Journal of Foshan University(Natural Science Edition)
基金
欧盟资助的国际合作项目
