摘要
目的 探讨原发性肝癌 (PHC )伴门静脉癌栓的有效治疗方法。方法 回顾性分析 2 3例原发性肝癌伴门静脉癌栓患者的临床资料。结果 2 3例均行手术切除肿瘤 ,并尽可能切除有癌栓的门静脉及从肝断面门静脉内取栓。术后分别采用化疗泵和微量泵化疗 ,并观察疗效。门静脉主干癌栓 8例 ,死亡 2例 ,6个月内复发 4例 ;门静脉第 1级分支癌栓 11例 ,6个月内复发 2例 ,6～ 12个月内复发 6例 ;小分支癌栓 4例 ,6～ 12个内复发 1例 (P <0 .0 1)。化疗泵化疗 12例 ,6个月内复发 5例 ,6～ 12个月内复发 4例 ;微量泵化疗 9例 ,6个月内复发 1例 ,6～ 12个月内复发 3例 (P <0 .0 1)。结论 手术治疗原发性肝癌伴门静脉癌栓有效 ;术后首选微量泵持续灌注化疗 ;
Objective To investigate an effective method of treating primary hepatic cancer(PHC) with portal venous tumor thrombosis (PVTT). Methods The clinical data Of 23 patients with PHC and PVTT were retrospectivly analysed. Results Of the 23 patieats after hepatoma resection and PVTT extraction, continuous micro dose infusion chemotherapy or perfusion chemotherapy by DDS was adopted. In 8 patients with main portal vein tumor thrombus, 2 died, 4 recured in 6 months. In 8 patients with the first class branch of portal vein tumor thrombus, 2 recurrd in 6 months and 6 recurred in 12 months. In 4 patients with secondary class branch of portal vein tumor thrombus, l recurred in 12 months (P<0.01) postoperatively .After operation, 17 patients underwent perfusion chemotherapy by DDS, 5 recurred in 6 months, 4 recured in 12 months; 9 patients underwent continuous micro dose infusion chemotherapy, 1 recured in 6 months, 3 recurred in 12 months (P<0.01). Conclusions (1) Operation is effective for treating HCC with PVTT. (2) Continuous micro dose infusion chematherapy is a main method of chemotherapy after operation. (3) treating efficacy is affected by the position of PVTT.
出处
《中国普通外科杂志》
CAS
CSCD
2001年第4期350-352,共3页
China Journal of General Surgery
关键词
治疗
并发症
门静脉
血栓形成
原发性肝癌
病因学
LIVER NEOPLASMS/ther
LIVER NEOPLASMS/compl
PORTAL, THROMBOSIS/edio
LIVER NEOPLASMS/surg
THROMBOSIS/surg
