摘要
[目的]探讨部分晚期喉癌全喉切除术前 ,进行喉裂开探查对病人的预后是否有影响。[方法]共收集资料齐全的191例全喉切除术病例 ,其中有29例进行了术前的喉裂开探查 ,比较有无术前探查两组病例的生存率、局部和区域淋巴结复发率。[结果]从总体上比较 ,术前探查和未探查组的总体生存时间差异无显著性意义 (LogRank统计值1.23,P=0.2682) ,在T3 病例中两组差异也无显著性意义 (LogRank统计值0.01,P=0.9978) ,而在T4 病例中两组的差异有显著性 (LogRank统计值3.94,P=0.047) ;从总体上看 ,两组局部和区域淋巴结复发率也没有统计学差异 ( χ2 值分别是0.099和0.025,P值分别是0.753和0.874)。[结论]在T3 喉癌病例中 ,全喉切除术前进行喉裂开探查是较安全的方法 ,对患者的预后无明显影响 ,而在T4 喉癌中其应用要慎重。
PurposeTo investigate the impact of exploratory surgery before total laryngectomy on the prognosis in patients with laryngeal carcinoma.191 cases of laryngeal carcinoma were collected. Among them,there were 29 cases with exploratory surgery. The recurrent rate,node metastasis and survival were compared between patients with and without exploration.No significant difference was found in the survival between the two groups (log rank=1.23,P=0.2682),also in the T3 cases (log rank=0.01,P=0.9978),but it was significant difference in the T4 cases (log rank=3.94,P=0.047);There was no significant difference in local metastasis or node metastasis between the two groups (χ2 0.099 and 0.025,P value 0.753 and 0.874).[Conclusions]The exploratory surgery before total laryngectomy in T3 laryngeal carcinoma is a safe way,but no impact on prognosis in T4 cases.
出处
《中国肿瘤》
CAS
2001年第9期550-552,共3页
China Cancer
关键词
喉肿瘤
全喉切除术
探查术
预后
laryngeal neoplasms
total laryngectomy
exploratory surgery
prognosis
