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卵巢保守性手术后卵巢早衰临床分析 被引量:29

Clinical study on premature ovary failure after ovarian conservative operation.
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摘要 目的 :研究卵巢保守性手术引起卵巢早衰的原因。方法 :选择因卵巢保守性手术引起卵巢早衰 6例为研究组 ,同期行卵巢保守性手术后卵巢功能正常 6例为对照组 ,观察术后月经变化 ,临床症状 ,促性腺激素及性激素水平 ,B超测定所得卵巢体积 ,手术方式 ,术中所测囊肿大小和术中出血量。结果 :因卵巢保守性手术引起意外绝经的病例 ,均为双侧卵巢手术 ,且多行单侧附件切除加对侧囊肿挖除术 ;与对照组相比 ,卵巢早衰组术后保留的正常卵巢组织显著小 (P <0 .0 5 ) ;术中所测卵巢囊肿体积明显大 (P <0 .0 5 ) ;术中出血量显著多于对照组 (P <0 .0 1)。结论 :术前囊肿较大 ,术后残留正常卵巢组织过少和术中损伤卵巢较大血管是卵巢保守性手术后发生早衰的主要原因。年轻妇女尤其是有生育要求者 ,应尽早手术 ,行卵巢保守性手术时原则上不切除单侧卵巢 ,尽量保留正常卵巢 ,术中避免损伤卵巢主要血管 。 Objective:To investigate the cause of premature ovary failure(POF) after ovarian conservative operation.Methods:6 cases of POF after ovarian conservative operation were studied.The menstrual changes,symptoms,level of gonadotropin and sex hormone,residual ovarian volume after surgery,size of the ovarian cyst,operation style and hemorrhage during operation were observed.Results:All operation-caused POFs went on bilateral surgery and most of them included unilateral adnexectomy.The residual ovarian volume was significantly smaller and the size of ovarian cyst was larger than that of control group.The hemorrhage during surgery was significantly much more than that of control group. Conclusions:Larger ovarian cyst,less residual ovary and damage of large ovarian vessel during operation are the main causes of POF after operation.To avoid this,conservative ovarian surgery should be done earlier and a residual normal ovary should be more as possible as it can be done.Also damage of large ovarian vessel should be avoided.To young childbearing-age women,unilateral adnexectomy should not be done primarily,especially to those who want to get pregnant.Too much tight sewing and binding should be avoided.
出处 《现代妇产科进展》 CSCD 2001年第4期261-263,共3页 Progress in Obstetrics and Gynecology
关键词 卵巢保守性手术 卵巢早衰 闭经 Ovarian conservative surgery Premature ovary failure Amenorrhea
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  • 1英J·B·斯坦莱克 著沈文梅药物作用的化学基础[M].

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