摘要
神经营养因子对神经元生长发育的影响逐渐被认识并得到重视 ,尤其是神经生长因子家族中的神经生长因子、脑源性神经营养因子、胶质细胞源性神经营养因子倍受重视。它们在脑缺血损伤过程中的作用 ,不仅表现在对缺血损伤的神经元具有防止发生凋亡的作用 ,而且能促进残存的神经元建立新的突触联系 ,促进神经功能的恢复。
出处
《国外医学(脑血管疾病分册)》
2001年第3期159-161,共3页
Foreign Medical Sciences Cerebrovascular Diseases
参考文献16
-
1Semkova I, Krieglstein J. Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors. Brain Res Brain Res Rev. 1999, 30(2): 176-188.
-
2Boris Moller F, Kamme F, Wieloch T. The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat. Brain Res Mol Brain Res, 1998,63(1):163-173.
-
3Cui JK, Hsu CY, Liu PK. Suppression of postischemic hippocampal nerve growth factor expression by a c-fos antisense oligodeoxynucleotide. J Neurosci. 1999, 19(4): 1335-1344.
-
4Abe K, Saito H. Neurotrophic effect of basic fibroblast growth factor is mediated by the p42/p44 mitogen-activated protein kinase cas cade in cultured rat cortical neurons. Brain Res Dev Brain Res.2000, 122(1 ): 81-85.
-
5Lin TN. Wang PY, Chi SI, et al. Differential regulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha (CNTFR alpha) expression following focal cerebral ischemia. Brain Res Mol Brain Res, 1998, 55(1): 71-80.
-
6Kumon Y, Sakaki S, Watanabe H, et al. Ciliary neurotrophic factor attenuates spatial cognition impairment, cortical infarction and thalamic degeneration in spontaneously hypertensive rats with focal cerebral ischemia. Neurosci Lett, 1996, 206(2-3): 141-144.
-
7Endres M, Fan G, Hirt L, et al. Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression. J Cereb Blood Flow Metab, 2000, 20(1 ): 139-144.
-
8Larsson E, Nanobashvili A, Kokaia Z, et al. Evidence for neuroprotective effects of endogenous brain-derived neurotrophic factor after global forebrain ischemia in rats. J Cereb Blood Flow Metab. 1999.19(11):1220-1228.
-
9Kiprianova I, Sandkuhler J, Schwab S, et al. Brain-derived neurotrophic factor improves long-term potentiation and cognitive functions after transient forebrain ischemia in the rat. Exp Neurol. 1999, 159(2): 511-519.
-
10Tremblay R, Hewitt K, Lesiuk H, et al. Evidence that brain-derived neurotrophic factor neuroprotection is linked to its ability to reverse the NMDA-induced inactivation of protein kinase C in cortical neurons. J Neurochem, 1999, 72(1): 102-111.
同被引文献8
-
1Desole MS, Sciola L, Sircana S, et al. Protective effect of deferoxamine on sodium nitroprusside-induced apoptosis in PC12 cells.Neuroscience Letters, 1998, 247:1 - 4.
-
2Guegan C, Ceballos PI, Chevalier E, et al. Reduction of ischemic damage in NGF-transgenic mice: correlation with enhancement of antioxidant enzyme activities. Neurobiologv of Disease, 1999, 6:180 - 189.
-
3Cha YK, Kim YH, AhnYH, et al. Epidermal growth factor induces oxidative neuronal injury in cortical culture. Journal of neurochemistry, 2000, 75:298 - 303.
-
4Leong SK, Ruan RS, Zhang Z. A critical assessment of the neurodestructive and neuroprotective effects of nitric oxide. Annals of the New York Academy of Sciences, 2002, 962:161 - 181.
-
5刘宏雁,赵红,王维忠,吕国尉.一氧化氮在缺氧耐受形成中的作用[J].中国应用生理学杂志,1998,14(2):147-149. 被引量:4
-
6陈谦,汪家政,范明.神经营养因子在神经损伤中的作用机制[J].神经解剖学杂志,1998,14(3):278-282. 被引量:29
-
7吴俊芳,王平,张均田.神经生长因子对一氧化氮介导的大鼠脑皮质神经元毒性的影响[J].中国生化药物杂志,1999,20(4):170-173. 被引量:7
-
8潘兴瑜,付京晶,薛欣,孙伟.MTT比色法改进的研究[J].中国免疫学杂志,1999,15(12):559-559. 被引量:35
二级引证文献2
-
1杨明峰,张颜波,孙保亮,牛敬忠,吕国蔚.低氧预适应小鼠脑匀浆液提取液对大鼠鼠胚海马神经元缺氧复氧后神经细胞的影响[J].中华神经医学杂志,2009,8(11):1094-1097. 被引量:10
-
2黄学文,李素芝,谢晓娥,黄跃,闫春城,殷作明,黄雪琴,吴亮,杨振翰.阶梯法与非阶梯法进入海拔4500m高原AHAD发病率调查[J].西南国防医药,2015,25(2):230-231. 被引量:5
-
1刘崴,程焱,王虔.脑源性神经营养因子与缺血性脑损伤[J].国外医学(脑血管疾病分册),2004,12(6):433-436. 被引量:10
-
2詹合琴,吴蓝鸥,王廷华.神经生长因子家族与脑缺血[J].国外医学(脑血管疾病分册),2004,12(3):208-211. 被引量:20
-
3苏红玉,胡建.酒依赖与神经生长因子家族及受体的相关研究进展[J].中华行为医学与脑科学杂志,2012,21(3):281-282. 被引量:1
-
4张顺清,吴爱群,张伟宏,岳新灿,曾光伟.氦氖激光对体外培养神经元生长发育的影响[J].中国临床康复,2005,9(1):88-90. 被引量:4
-
5曹艳华,白晓玲.兴奋性氨基酸及其受体在缺氧缺血性脑损伤中的作用[J].实用医药杂志,2005,22(3):254-255. 被引量:4
-
6陈兴泳,唐荣华,唐洲平.环磷酸腺苷反应元件结合蛋白与阿尔茨海默病[J].中国神经免疫学和神经病学杂志,2008,15(2):144-146. 被引量:2
-
7邓志云.GAP-43的研究进展及其与周围神经再生的关系[J].南昌大学学报(医学版),2012,52(6):94-97. 被引量:12
-
8咸海青,范明,刘红,刘淑红,杜方勇,甘思德.人睫状神经营养因子的原核高效表达[J].生物技术通讯,1995,6(1):49-49.
-
9曾茜,向虹雨,饶莹,胡析,曹蓝,张晓,梁楠.神经电刺激对大鼠脊髓钝挫伤后神经营养因子4和增殖细胞核抗原表达影响的研究[J].中国康复医学杂志,2015,30(11):1100-1104. 被引量:3
-
10陈强,侯凯.脑缺血/再灌注损伤过程中脑内脑源性神经营养因子和促凋亡因子与神经元凋亡的关系[J].长春中医学院学报,2004,20(1):47-49. 被引量:1