DIFFERENTIAL ROLES OF SPINAL CYCLOOXYGENASE (COX)-2 IN DEVELOPMENT OF PERSISTENT SPONTANEOUS NOCICEPTION AND HYPERALGESIA INDUCED BY SUBCUTANEOUS BEE VENOM INJECTION IN THE CONSCIOUS RAT 被引量：5

DIFFERENTIAL ROLES OF SPINAL CYCLOOXYGENASE (COX)-2 IN DEVELOPMENT OF PERSISTENT SPONTANEOUS NOCICEPTION AND HYPERALGESIA INDUCED BY SUBCUTANEOUS BEE VENOM INJECTION IN THE CONSCIOUS RAT

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摘要 Aim: To study the roles of spinal cyclooxygenase (COX) -2 in the development of persistent spontaneous nociception and mechanical and thermal hyperalgesia induced by subcutaneous(s.c.) bee venom injection, the effects of intrathecal (i.t.) administration of a selective COX-2 inhibitor, etodolac was evaluated in the conscious rat. Methods: Chronic intrathecal (i.t.) catheterization was performed and effects of i.t. pre-and post-application

作者 Zhen LI and Jun CHEN Department of Anatomy and K.K.Leung Brain Research Centre, The Fourth Military Medical University, Xi’an, 710032

出处《神经解剖学杂志》 CAS CSCD 北大核心 2001年第B07期103-103,共1页 Chinese Journal of Neuroanatomy

关键词大白鼠脊髓环氧化酶2 持续性自发性损伤感受痛觉过敏蜂毒皮下注射

分类号 R402 [医药卫生—临床医学]

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DIFFERENTIAL ROLES OF SPINAL CYCLOOXYGENASE (COX)-2 IN DEVELOPMENT OF PERSISTENT SPONTANEOUS NOCICEPTION AND HYPERALGESIA INDUCED BY SUBCUTANEOUS BEE VENOM INJECTION IN THE CONSCIOUS RAT 被引量：5

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