摘要
Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. Its structure was determined to be C 1 epimer of sarcophinone by spectroscopic methods. Bioassay showed that both sarcophinone(1) and iso sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.
Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. Its structure was determined to be C 1 epimer of sarcophinone by spectroscopic methods. Bioassay showed that both sarcophinone(1) and iso sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2001年第9期1515-1517,共3页
Chemical Journal of Chinese Universities
基金
国家自然科学基金 (批准号 :2 9772 0 5 8
2 992 0 30 )
"九五"国家科技专项"南沙群岛及其邻近海区综合科学考察"项目(批准号 :97-92 6 -0 2 -0 3)资助
