摘要
用取代吡唑醛与水合肼反应生成腙 ,后者与异氰酸酯、异硫氰酸酯反应 ,制得一系列新型 N-(1 -苯基 -3 -甲基 -5-氯 -4 -吡唑亚甲胺基 ) -N -苯基脲类化合物 ,其结构经 IR、1 H NMR、MS和元素分析确认 ,部分化合物生物活性普筛发现 ,一些缩胺硫脲有杀菌活性 .
The title compounds were synthesized from substituted pyrazolyl aldehyde as starting material, which were treated with hydrazine hydrate to give hydrazone(M-1). M-1 were reacted with isocyanates,isothiocyanates to yield 1~19. The structures of compounds were confirmed by elemental analyses, 1H NMR?IR and MS. The preliminary bioassay indicated that some of them displayed fungicidal activities.
出处
《应用化学》
CAS
CSCD
北大核心
2001年第7期513-516,共4页
Chinese Journal of Applied Chemistry
基金
国家自然科学重点基金资助课题 (2 983 2 0 5 0 )
