摘要
目的 :探讨电针“百会”、“三阴交”穴对慢性应激抑郁模型大鼠海马BDNF的影响。方法 :采用免疫组织化学的方法对BDNF阳性神经元进行染色 ,并用图像分析仪进行定量分析。结果 :慢性应激抑郁模型大鼠海马BDNF阳性神经元显著减少 ,形态以空泡为主 ,而电针对其有明显改善作用。结论 :电针对海马BDNF的保护作用 。
Objective to observe the effects of electro acupuncture of points “baihui” (D20) and “sanyinjiao”(S6) on hippocampus brain derived neurotrophic factor in the animal model of chronic stressed depression. Method with the method of immuno histochemistry therapy to measure the BDNF neurons. Results immuno histochemistry results showed that the number of infected neurons of depressed animals was much less than that of normal animals. electro acupuncture can increase the number of BDNF neuron on hippocampus in the depressed animal. Conclusion Electro acupuncture may cure depression by protecting the BDNF neurons in hippocampus.
出处
《中国中医基础医学杂志》
CAS
CSCD
2001年第7期55-57,共3页
JOURNAL OF BASIC CHINESE MEDICINE
关键词
电针
抑郁症
脑源性神经营养因子
免疫组织化学法
治疗
electro acupuncture
depression
brain derived neurotrophic factor
immuno histochemistry
