摘要
目的 减少对乳腺癌的漏诊 ,降低假阴性诊断 ,提高针吸细胞学诊断的准确性。方法 对 72 31例乳腺肿块进行针吸细胞学检查 ,获取病理组织学对照有 744例 ,计算其细胞学诊断的敏感性、特异性、假阳性率、假阴性率、诊断符合率。结果 本组针吸细胞学诊断敏感性为 93 6 7% ,特异性为 96 43 % ,假阳性率为 3 5 7% ,假阴性率为 6 33 % ,符合率为 94 0 9%。结论 针吸细胞学诊断的敏感性及特异性强 ,符合率高 ,是一种乳腺肿块重要的辅助诊断方法。肿瘤实质细胞较少或细胞异型性不明显是假阴性诊断的主要原因。注意触诊 ,重复针吸是减少假阴性的主要措施。
Objective The aim is to reduce missed diagnosis and false negative diagnosis,and to improve the accuracy of fine needle aspiration cytology (FNAC).Methods 744 of 7 231 patients with a breast lump were subjected to concurrent FNAC and biospy,to gain contrast and to compute the sensitivity,specificity,false positive rate,false negative rate and concordance rate of cytology diagnosis.Results We gained the results as follows:93.67% for sensitivity,96.43% for specificity,3.57% for false positive rate,6.33% for false negative rate and 94.09% for concordance rate.Conclusions FNAC is an important assistant diagnostic method which is highly sensitive and specific and has concordance rate.The main reason for interpretive errors in false negative diagnosis is hypocellularity or unobvious nuclear polymorphism.Palpation and repleated FNAC can reduce false negative rate.
出处
《河南肿瘤学杂志》
2001年第4期254-255,共2页
Henan Journal of Oncology
