摘要
目的 了解不同分期的肺癌病人的血液流变学变化及临床意义。方法 对 48例肺癌及 5 2例健康者血液流变学相关指标进行比较并对不同分期的肺癌病人血液流变学指标比较。结果 肺癌病人全血低切、高切粘度、血浆粘度比及血沉差异均有极显著性 (P <0 0 1) ,红细胞压积差异无显著性 (P >0 0 5 ) ;Ⅳ期病人较Ⅰ期病人高切、低切粘度差异显著 (P <0 0 5 ) ,血浆粘度比及纤维蛋白原差异极显著 (P <0 0 1)。结论 肺癌病人在不同时期都有明显血液流变学改变 ,如能对早、中期病人血粘度异常进行适当治疗 ,则能减少和预防肺癌的血行转移及复发 ,对晚期病人则不宜降低血粘度。
Objective To detect the changes of hemorrheological state in patients with different states of lung cancer and its clinical significance.Methods Hemorrheological indicators were measured in healthy persons (n=52) and patients with different states of lung cancer.Results In patients with lung cancer,levels of whole blood low shear rate,high shear rate,plasma viscosity and erythrocyte sedimentation were significantly different from those in healthy persons ( P <0.01).Hematocrit didn't have such significant difference ( P >0.05).The levels of whole blood low shear rate and high shear rate were greatly changed in stage Ⅳ lung cancer patients ( P <0.05).The levels of whole blood plasma viscosity and Fib were changed in stage Ⅳ lung cancer patients ( P <0.01).Conclusions The hemorrheological state is abnormal in patients with lung canaer.Proper treatment of abnormal hemorrheological state of early and middle stage lung cancer patients may reduce and prevent the metastasis and recurrence of lung cancer.Advanced lung cancer patients shouldn't reduce blood viscosity.
出处
《河南肿瘤学杂志》
2001年第4期242-243,共2页
Henan Journal of Oncology
关键词
肺癌
不同时期
血液流变学
lung cancer
different states
hemorrheology.
