摘要
目的 探讨溶栓治疗急性脑梗死的最佳途径、时间、药物的剂量、安全性及适应症。方法 对急性脑梗死患者 ,随机进行超选择性动脉灌注尿激酶溶栓治疗 30例和单纯静脉溶栓治疗 32例对照研究。结果 动脉溶栓总有效率为 80 % ,平均住院 14.3± 5 .6天 ;静脉溶栓总有效率为 5 3.13% ,平均住院 2 2 .6± 4.8天 ,两组比较有显著性差异 (P<0 .0 5 )。尿激酶 (U K)的用量与出血并发症的发生率成正比。结论 急性脑梗死早期动脉溶栓疗效显著 ,且较静脉溶栓效果好。对于轻型神经功能缺损的患者 ,不主张动脉溶栓治疗。 U K单次用量不宜超过 5 0万
Objective To discuss thrombolytic therapy of actute cerebral infarction in preferred way,time,thrombolytic dosage,safility and indications.Methods A random control study was made by supperselected intraaterial thrombolysis in 30 cases and venous thrombolysis in 32 cases respectively.Results The total effective rate and the average hospitalizationis were 80% and 14.3±5.6 days in the aterial group while 53.13% and 22.6±4.8 days in the venous group respectively.There were significant different between tow groups ( P <0.05).Urodinase's dosage and the hemorrhage incidence were in direct ratio.Conclusions The curative effect was much more significant in early supperselected intraaterial thrombolysis group.However,it was not suitable for the cases with light dysneuria.Urodinase single should be under 500 000IU.
出处
《北京医学》
CAS
北大核心
2001年第3期154-156,共3页
Beijing Medical Journal
