摘要
应用正反双向血凝试验对210例伤寒病人进行了研究,并与血培养、肥达试验作了比较分析,同时调查了142例非伤寒病人和348名正常人的血凝滴度。研究结果显示,本法的敏感性、特异性、早期(发病1周内)检出率分别为97.89％,98.4％和96.2％,假阳性率为5.59％;肥达试验分别为76.4％,77.0％,50.0％和29.9％。两法比较均有显著的统计学意义(P均<0.01)。以上结果提示,本方法具有敏感性高、特异性强的特点,对伤寒病的早期诊治具有重要的临床价值。
The indirect haemagglntination (IHA) and reverse indirect haemagglutination (RIHA) test were used to detect the presence of Salmonella typhic antigens and antibodies in the sera of 210 cases of typhoid fever, and the results were compared with blood culture and Widal test. At the same time the haemagglutination liters were assayed in the sera of 142 cases nontyphoid patients and 348 healthy individuals. The findings showed that the sensitivity, specificity, early detection rate and false positive rate of this assay were 97.8%, 98.4%, 96.2% and 5.5%, respectively, while that of the Widal test were 76.4%, 77.0%, 50.0%, and 29.9%, respectively. The difference between these two tests was statistically significant (all P<0.01),suggesting that IHA and RIHA had a good sensitivity and specificity. Therefore, IHA and RIHA tests are valuable in early diagnosis of typhoid fever.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
1991年第2期81-84,共4页
Medical Journal of Chinese People's Liberation Army
关键词
伤寒病
血凝法
血清学诊断
Typhoid fever Serological diagrsis Haemagglutination tests
