摘要
作者对529例各型肝病患者的血清检测了丁型肝炎病毒(HDV)标志(包括HDAg、抗HD、抗HD IgM)。发现慢性活动型肝炎的HDV标志阳性率(48/176例,27.3％)最高,HDV促进形成慢性活动型肝炎的可能性极大。本组原发性肝癌中HDV标志阳性率亦达20％,提示HDV能加强乙型肝炎形成恶变。本组发现4例HDV标志阳性者虽长期观察(其中1例观察4年)亦未发现乙型肝炎标志,系缺陷病毒有独立感染抑或与HCV重叠感染未明,但5例均无输血史。
Serum screening of HDV markers (including HDAg, anti-HD and anti-HD IgM) in 529 cases of various clinical types of hepatitis demonstrated that the highest incidence of HDV markers was found in chronic active hepatitis B (48/176 or 27.3%). Also it is worthy of note that the incidence of HDV in the hepatocellular carcinoma patients was also as high as to 20 percent. It is suggested that the HDV infection may play a role in provoking the HBV infection to become malignent. In 4 HDV positive patients, their HBV markers were persistently negative (one of them was followed for 4 years). It was suspected that under certain conditions the defective virus (HDV) may infect the human body by itself without the coinfection of HBV.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
1991年第2期110-112,共3页
Medical Journal of Chinese People's Liberation Army
关键词
乙型肝炎
丁型肝炎
病因
Hepatitis B Hepatits D HDAg Anti-HD Anti-HD IgM
