摘要
目的:研究2型糖尿病(DM)合并肝损害患者降糖治疗前后肝功能及血脂变化。方法:对45例2型DM合并肝损害患者采用降糖药物治疗,并测定其治疗前后血生化相关指标的变化。结果:2型糖尿病合并肝损害患者TC、AST、ALT、TBIL、HA、SF、sIgA经降糖治疗后低于治疗前(P<0.01),而TG、ALB、GLO无明显变化(P>0.05)。结论:2型DM合并肝损害患者,经降糖治疗后能够改善肝功能。2型DM患者常规进行肝功能检测是非常必要的。检测血清HA、SF、sIgA水平对于了解肝功能情况有一定的临床价值。
To observe the changes of liver function and blood-lipid in 45 type 2 diabetic patients with hepatic in jury before and after hypoglycemic treatment. Methods: The changes of serum total glycerol(TG), total cholesterin(TC), as-partate aminotransferase(AST), alanine aminotransferase(ALT),albumin(ALB) , globulin(GLO) , total bilirubin(TBIL), hyaluronic acid(HA), serum ferritin(SF) and secrete immunoglobulin A (slgA) of these patients were detected before and after hypoglycemic treatment. Results: The serum AST, ALT, TBIL, HA, SF and slgA were significantly decreased after treatment (P < 0.05 ) , but the serum TG, TC, ALB and GLO did not change (P > 0.05 ). Conclusion; The liver function of type 2 diabetic patients with hepatic injury can be improved by the hypoglycemic treatment. It is necessary for type 2 diabetic patients to check the liver function. Measuring the levels of serum HA, SF and slgA is possessed of clinical value for understanding the liver function.
出处
《天津医药》
CAS
北大核心
2001年第9期538-539,共2页
Tianjin Medical Journal
关键词
非胰岛素依赖型糖尿病
肝疾病
降血糖药
治疗
diabetes mellitus, non-insulin-dependent liver diseases hypoglycemic agents
