摘要
本文介绍了急性肺损伤及炎症的药物治疗方面的研究进展 ,叙述了细胞因子抗体、抑制剂、受体拮抗剂、蛋白酶抑制剂、以及活性氧相关治疗的作用机制和临床治疗应用。这些研究进展对急性肺损伤的药物治疗研究有极大的促进作用。
出处
《国外医学(药学分册)》
2001年第4期213-217,共5页
Foreign Medical Sciences(Section of Pharmarcy)
参考文献20
-
1[1]Berleth ES, Nadadur S, Henn AD. Identification, characterization, and cloning of TIP-B1, a novel protein inhibitor of tumor necrosis factor-induced lysis [ J ]. Cancer Res,1999, 59(21) :5497 - 5506.
-
2[2]Dinarello CA, Thompson RC. Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro [ J ] . Immunol Today, 1991, 12(11):404-410.
-
3[3]Nagase T, Ishii S, Kume K, et al. Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice[J]. J Clin Invest, 1999, 104(8): 1071 - 1076.
-
4[4]Mazer BD, Toledano B, Saririan M, et al. Dose-dependent agonist and antagonist effects of the platelet-activating factor analogue 1- palmitoyl-2-acetoyl-Sn- glycero-3-phosphocholine on B lymphocytes[J]. J Allergy Clin Immunol, 1998, 102(2) :231 - 237.
-
5[5]de la Cruz P, Moreno A, Ruiz-Ruiz MI, et al. Effect of WEB2086-BS, an antagonist of platelet-activating factor receptors, on retinal vascularity in diabetic rats [ J ]. Eur J Pharmacol, 1998, 360(1):37 -42.
-
6[6]Yamano M, Umeda M, Miyata K, et al. Protective effects of a PAF receptor antagonist and a neutrophil elastase inhibitor on multiple organ failure induced by cerulein plus lipopolysaccharide in rats [ J ]. Naunyn Schmiedebergs Arch Pharmacol, 1998, 358(2) :253 - 263.
-
7[7]Weber C, Erl W, Pietsch A, et al. Aspirin inhibits nuclear factor-κB mobilization and monocyte adhesion in stimulated human endothelial cells [ J ]. Circulation, 1995, 91 (7):1914- 1917.
-
8[8]Huang ZH, Bates EJ, Ferrante JV, et al. Inhibition of stimulus-induced endothelial cell intercellular adhesion molecule-1, E-selectin, and vascular cellular adhesion molecule-1 expression by arachidonic acid and its hydroxy and hydroperoxy derivatives[J]. Circ Res, 1997, 80(2):149- 158.
-
9[9]Bennett CF, Kornbrust D, Henry S, et al. An ICAM-1 antisense oligonucleotide prevents and reveres dextran sulfate sodium-induced colitis in mice[J]. J Pharmacol Exp Ther,1997, 280(2) :988 - 1000.
-
10[10]Ohara M, Sawa T, Kurahashi K, et al. Induction of cyclooxygenase-2 in alveolar macrophages after acid aspiration [J]. Anesthesiology, 1998, 88(4):1014-1022.
同被引文献19
-
1张玉心,马涛,韩玲,丁廷波,杨渝珍.LPS对金属蛋白酶的诱导表达及中药热毒清的保护机制[J].癌变·畸变·突变,2006,18(4):294-297. 被引量:1
-
2Merinen M,Irjala H,Salmi M,et al.Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse[J].Am J Pathol,2005,166(3):793-800.
-
3Salmi M,Jalkanen S.VAP-1:an adhesin and an enzyme[J].Trends Immunol,2001,22(4):211-216.
-
4Smith DJ,Salmi M,Bono P,et al.Cloning of vascular adhesion protein 1 reveals a novel multifunctional adhesion molecule[J].J Exp Med,1998,188(1):17-27.
-
5Stolen CM,Marttila-Ichihara F,Koskinen K,et al.Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivo[J].Immunity,2005,22(1):105-115.
-
6Boomsma F,Bhaggoe UM,van der Houwen AM,et al.Plasma semicarbazide-sensitive amine oxidase in human (patho)physiology[J].Biochim Biophys Acta,2003,1647(1-2):48-54.
-
7Yu PH,Lu LX,Fan H,et al.Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in lipopolysaccharide-induced pulmonary inflammation[J].Am J Pathol,2006,168(3):718-726.
-
8Singh B,Tschernig T,van Griensven M,et al.Expression of vascular adhesion protein-1 in normal and inflamed mice lungs and normal human lungs[J].Virchows Arch,2003,442(5):491-495.
-
9Li H,Luo WH,Lin JJ,et al.Assay of plasma semicarbazide-sensitive amine oxidase and determination of its endogenous substrate methylamine by liquid chromatography[J].J Chromatogr B Analyt Technol Biomed Life Sci,2004,810(2):277-282.
-
10Salter-Cid LM,Wang E,O' Rourke AM,et al.Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazidesensitive amine oxidase[J] J Pharmacol Exp Ther,2005,315(2):553-562.
二级引证文献5
-
1门华涛,罗红军,李慧,罗文鸿.兔血浆SSAO的分离纯化及其酶动力学研究[J].癌变·畸变·突变,2008,20(5):385-388. 被引量:1
-
2潘梅,罗坚.HPLC梯度洗脱法测定西维来司他钠的含量及有关物质[J].生命科学仪器,2008,6(7):47-49.
-
3张迎庆,糜志远,王攀,熊维德.紫外分光光度法测定注射用西维来司他钠的含量[J].海峡药学,2008,20(7):62-63.
-
4郑翔,曹霞飞,王敏,李程,张鹏,让蔚清.白藜芦醇抗炎作用与氨基脲敏感性胺氧化酶活性的关系[J].营养学报,2010,32(6):560-563. 被引量:3
-
5王晶,戴晓健,张逸凡,钟大放,吴玉林,陈笑艳.LC-MS/MS法同时测定人血浆中西维来司他及其代谢物[J].药学学报,2015,50(10):1318-1323. 被引量:1
-
1刘枧根.急性冠脉综合征患者采用阿托伐他汀治疗的疗效与药理解析[J].基层医学论坛,2016,20(36):5088-5089. 被引量:1
-
2徐占领.冠心病并慢性充血性心力衰竭中应用曲美他嗪的临床治疗应用[J].中国现代药物应用,2010,4(23):105-106. 被引量:6
-
3张雯,宋俊科,杜立达,张雪,杜冠华.急性脑缺血治疗药物研究进展[J].神经药理学报,2014,4(4):50-58. 被引量:13
-
4卢钰.非洛地平运用于高血压临床治疗的分析[J].中西医结合心血管病电子杂志,2014,2(11):179-179. 被引量:2
-
5蔡颖.支气管哮喘的免疫治疗进展[J].世界临床药物,2006,27(1):29-31. 被引量:8
-
6周旋.氨溴索雾化吸入治疗慢性肺源性心脏病的效果观察[J].国际医药卫生导报,2015,21(8):1125-1126. 被引量:3
-
7赵甲军.阿奇霉素治疗化脓性扁桃体炎的临床疗效观察[J].中国卫生标准管理,2016,7(10):120-121. 被引量:4
-
8吕亚新,罗蔓菲.瑞舒伐他汀的药理分析及抗动脉粥样硬化的临床应用价值[J].养生保健指南(医药研究),2016,0(1):40-40.
-
9陶然,黄红光,高利臣.高血压药物的不良反应与药物基因组学关系的研究进展[J].中国临床药理学与治疗学,2014,19(10):1183-1188. 被引量:15
-
10陶维祝.无创正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭疗效观察[J].大家健康(学术版),2014(24):149-150. 被引量:1