摘要
目的 研究慢性特发性便秘 (CIC)患者的肛门直肠动力学及其心理的变化。方法 肛门直肠测压法检测 2 8例CIC患者肛门直肠动力学的变化 ,同时进行心理测试 ,并与 2 4名健康者进行对照观察。结果 CIC患者年龄偏大 ( P <0 .0 5) ;肛门括约肌静息压、最大缩榨压降低 ( P <0 .0 5,P <0 .0 0 5) ;肛管高压带长度增加 (P <0 .0 0 5) ;引起直肠肛门抑制反射的最小松弛容量(MVR)增加 (P <0 .0 0 5) ,肛门括约肌松弛率下降 (P <0 .0 2 5) ;直肠内部容量刺激的排便阈值和最大耐受量均明显增加 (P <0 .0 0 5,P <0 .0 0 5) ;CIC患者焦虑、抑郁精神心理异常倾向的出现率明显高于对照组 (P <0 .0 5,P <0 .0 1 )。结论 CIC患者存在肛门直肠动力学及精神心理因素的异常。
Objective To investigate the changes of anorectal motility and psychical factors in patients with chronic idiopathic constipation (CIC). Methods Anorectal manometry was carried out in 28 CIC patients by using Medtronic Synectics PC Polygraf, while time the psychical factors were tested. 24 normal controls were also studied. Results CIC patients were older than controls(P<0.05), showed lower anorectal sphincteric resting pressure (P<0.05) and lower anorectal sphincteric squeezing pressure (P<0.005) ,longer length of anal high pressure zone (P<0.005), larger minimum relaxation volume to elicit the anorectal inhibitory reflex (P<0.005), lower relaxation of internal anal sphincter (P<0.025), higher rectal defecatioon volume thresholds (P<0.005) and higher rectal maximum tolerable volume thresholds (P<0.005) with respect to controls. In the aspect of psychical testing, the rate of psychical abnormalities was higher in CIC patients compared with controls (Anxiety: P<0.05; Depression:P<0.01). Conclusion Patients with CIC have abnormalities both in anorectal motility and psychical factors.
出处
《临床内科杂志》
CAS
北大核心
2001年第5期379-381,共3页
Journal of Clinical Internal Medicine
关键词
便秘
肛门直肠测压
精神因素
Constipation
Anorectal motility
Psychical factor
