摘要
目的 : 研究在中国典型膳食条件下乙二胺四乙酸铁钠 ( Na Fe EDTA)中铁在人体的吸收率。方法 : 采用铁稳定性同位素54 Fe和58Fe分别标记 Fe SO4 和 Na Fe EDTA并以稀土元素镝 ( Dy)作为排泄物回收标记物。自愿受试者为 1 8～ 2 2岁健康女性。采用我国典型城镇成年女性膳食模式。两种铁剂和 Dy以酱油为食物载体一同分两天 6次经口给入。实验期间每日留取受试者膳食样品并收集受试者在实验期的粪便。采用原子吸收 ( AAS)和等离子体质谱 ( ICP- MS)分别检测膳食和粪便中总铁含量和铁同位素比例 ,对两种铁剂中铁的吸收率进行比较。结果 : Fe SO4 的铁平均吸收率为 4.73% ,而 Na Fe EDTA为 1 0 .51 % ,两者差异为极显著 ( P<0 .0 1 )。结论 : Na Fe EDTA中铁的吸收率优于 Fe SO4 。
Objective: The absorption of iron from NaFeEDTA and FeSO 4 was studied in 10 healthy female volunteers, aged 18 22 y.[WT5FZ]Methods: Stable iron isotopes 54 Fe and 58 Fe were used as tracers to label FeSO 4 and NaFeEDTA respectively. Dy was used as a marker of iron recovery. The diet used in the study was based on the typical dietary pattern of urban Chinese adult women. Soy sauce as the food vehicle of 54 FeSO 4 and Na 58 FeEDTA and Dy was orally administrated three times a day in two days. The diet and feces samples of subjects were collected for 15 consecutive days. AA and ICP MS were used for determination of iron and stable iron isotope concentration in food and feces samples. Results: The absorption rate of 54 Fe and 58 Fe were 4.73% and 10.51% respectively (P<0.01).Conclusion: The iron absorption rate of Fe from NaFeEDTA is significantly higher than that from FeSO 4 in a typical diet of urban Chinese adult women.
出处
《营养学报》
CAS
CSCD
北大核心
2001年第2期126-129,共4页
Acta Nutrimenta Sinica
基金
国际生命科学学会资助
关键词
乙二胺四乙酸铁钠
硫酸亚铁
稳定性同位素铁
稳定性同位素示踪法
铁吸收率
ethylenediamine tetraacetic acid ferric sodium salt
ferrous sulfate
iron stable isotopes
isotope trace method
absorption rate of iron
