摘要
目的 :探讨牙周洁治前后唾液中前列腺素 (PGs)变化 ,分析牙周洁治与PGs的关系。方法 :选慢性牙周炎(CP)患者 19例、青少年牙周炎 (JP)患者 11例 ,牙龈炎和健康人各 10例 ,用放射免疫测定法分析牙周洁治前后患者唾液中 6 -酮 -前列腺素F1a (6 -K -PGF1a)和前列腺素E2 (ProstaglandinE2 ,PGE2 )含量变化。结果 :洁治后牙周炎组患者唾液中 6 -K -PGF1a和PGE2 较治疗前明显降低 ,牙龈炎组患者唾液中 6 -k -PGF1a和PGE2 含量较洁治前降低最明显 ,健康人组唾液中 6 -K -PGF1a和PGE2 含量较治疗前轻度降低。洁治后CP组患者唾液中 6 -K-PGF1a和PGE2 较治疗前明显降低 ,而对JP患者降低程度较CP明显降低。结论 :牙周洁治对牙龈炎患者唾液中PGs降低程度最强 ,对牙周炎和健康人有一定降低作用 ,对JP患者降低程度最差。牙周洁治的作用机理可能与调节机体唾液中的PGs有密切关系。
Objective:To study the relationship between periodontal scaling and the contents of 6-Keto-Prostaglandin F1a (6-K-PGF 1a ) and prostaglandin E 2 (PGE 2) in salivary with periodontal diseases.Methods:19 cases chronic periodontitis(CP)、11 cases juvenile periodontitis(JP)、10 cases gingivitis and 10 cases health were selected,and measured the contents of 6-K-PGF 1a and PGE 2 in saliva of each patient by radioimmunoassay and analyzing the difference between scaling before and scaling after.Results:The contents of 6-K-PGF 1a and PGE 2 in saliva of group periodontitis were more significant reduced after scaling.The contents of 6-K-PGF 1a and PGE 2 in saliva of group gingivitis after scaling were decreased more severely than before scaling.But that of group health decreased less after scaling.There was no significant difference between group gingivitis and group health.The contents of 6-K-PGF 1a and PGE 2 in saliva with CP after scaling were decreased more severely than before scaling,but that of JP were not.Conclusions:There were more decreased effects of periodontal scaling to the contents of PGs with different periodontal diseases,and the decreased effects to PGs of group gingivitis were bigger than others.And there were some decreased effects to group periodontitis and group health,and fewer effects to group JP.The mechanisms of scaling more related to the contents of PGs in saliva. [
出处
《口腔医学纵横》
CAS
CSCD
2001年第2期125-127,共3页
Journal of Comprehensive Stomatology
基金
国家自然科学基金!资助课题 (编号3870 831)
关键词
牙周洁治
牙周病
前列腺素类
放射免疫测定
Periodontal scaling Periodontal diseases Prostaglandins Radioimmunoassay
