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肿瘤反基因治疗研究进展 被引量：3

Progresses in tumor antisense gene therapy
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摘要 寡聚核苷酸及其衍生物能选择性调节基因表达。在反义技术中 ,寡聚核苷酸可以mRNA的专一序列或双链DNA的特定序列为靶点 ,阻止遗传信息向蛋白质的流动 ;也可与双螺旋DNA专一序列结合形成三链DNA ,阻止基因转录或DNA复制。反基因寡聚核苷酸以其独特的结构和优于反义RNA的技术特点 ,为恶性肿瘤的治疗提供了新的途径。
作者 田长海 李祺福 欧阳高亮 洪水根
机构地区 厦门大学生命科学学院细胞生物学研究室
出处 《国外医学（肿瘤学分册）》 2001年第4期274-276,共3页 Foreign Medical Sciences (Cancer Section)
关键词 三链DNA 反基因 基因治疗 肿瘤治疗
分类号 R730.5 [医药卫生—肿瘤]
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参考文献10

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同被引文献22

  • 1李美华,朱贤立,赵洪洋.星形细胞肿瘤PCNA、p53蛋白表达与细胞增殖和肿瘤预后[J].中国临床神经外科杂志,2000,5(z1):43-44. 被引量：2
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引证文献3

二级引证文献4

国外医学（肿瘤学分册）
2001年 第4期

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