摘要
目的研究儿童恙虫病C反应蛋白 (CRP)的变化其诊断价值。方法测定 2 3例恙虫病患儿组与 2 2例对照组的血CRP ,比较二组间的差异、确定CRP诊断的敏感度、特异度 ;并比较恙虫病组中伴肝功能损害者 (A )和伴血沉增快者 (B)及无A、B变化的患儿 (C)之间CRP测定值的差异。结果恙虫病患儿组与对照组间血CRP测定值的对数转换均值分别为 1.6835± 0 .30 ,0 .95 47±0 .66,差异有显著性 (t =4.72 9,P <0 .0 1) ;CRP的敏感度和特异度分别为 87% ,72 % ,A、B、C三者之间无显著性差异。结论儿童恙虫病血CRP显著升高 ,CRP可以作为儿童恙虫病的早期诊断指标之一。
ObjectTo investigate the changes of C-reactive protein (CRP) and their diagnostic significance in children with scrub fever.MethodsThe blood levels of CRP were estimated in 23 children with scrub fever and 22 healthy controls. The difference between the results of two groups was compared to determine the sensitivity and specificity of CRP in diagnosis. In addition, the blood levels of CRP were compared among children with scrub fever accompanied with damage of liver function (group A), those accompanied with elevation of ESR (group B) and those without changes in group A and B (group C). ResultsThe average logarithmic changes of blood CRP levels in children with scrub fever and controls were 1.6835±0.30 and 0.9547±0.66, showing statistically significant difference as compared with each other (t=4.729,P<0.01). The sensitivity and specificity of CRP were 87% and 72% respectively. No statistic difference existed among group A, B and C. ConclusionThe blood levels of CRP markedly increased in children with scrub fever. CRP can be used as one of the criteria for its early diagnosis.
出处
《湖南医学》
2001年第4期256-257,共2页
Hunan Medical Journal
