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抑癌基因PTEN研究现状与展望 被引量:5

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摘要 PTEN基因是由 Steck等在 1997年克隆到的一个候选的抑制基因 ,定位于 10 q2 3.3,该基因的突变与缺失与人类多种肿瘤的发生发展及预后有关。本文对
出处 《国外医学(遗传学分册)》 CAS 2001年第4期190-194,共5页 Foreign Medical Sciences(Section of Genetics )
基金 福建省自然科学基金 94A0 10
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同被引文献94

  • 1邓杰,曹敦文,刘铭球,朱润庆,陈洪雷,陈道英,王冀鄂.p73、PTEN和Ki-67在子宫内膜样腺癌组织中的表达及意义[J].肿瘤防治研究,2006,33(11):811-813. 被引量:5
  • 2LAX S F, KENDALL B, TASHIRO H, et al. The trequency of p53, Kras mutations, and microsatel/ite instabiliey differs in utenine endonetroid and serous carcinoma. Evidence of diseinct molecdlar genetic pathwas[J]. Cancer, 2000, 88:814-824.
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  • 7Steck PA,Pershous MA, Jasser SA, et al.dentification of a candidat tumor suppressor gene, MMAC ,at chromosome 10q23.3 that ismutated in multiple advanced cancer[J].Nat Genet, 1997,15:356.
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