摘要
目的 探讨鼻咽癌咽旁间隙受侵对患者预后的影响。方法 1987年 1月～ 1994年 12月间对 197例初程治疗的鼻咽癌患者进行CT扫描检查 ,利用SPSS 8.0软件进行单因素和多因素分析影响预后的因素。结果 咽旁间隙受侵对实际生存、无瘤生存及局部控制有影响 (P =0 .0 115 ,P =0 .0 0 35 ,P =0 .0 36 7)。咽旁间隙阴性患者的 5年实际生存率、无瘤生存率和局部控制率分别为87.9%、88.0 %和 96 .9% ,茎突前间隙受侵分别为 75 .0 %、71.2 %和 93.7% ,茎突后间隙受侵分别为6 0 .5 %、5 7.7%和 86 .8%。结论 咽旁间隙受侵影响生存及局部控制 ,当茎突后间隙明显受侵时 ,远处转移的机会增加。
Objective To explore the prognostic influence of parapharyngeal space involvement in nasopharyngeal carcinoma (NPC).Methods From Jan.1987 to Dec. 1994, 197 previously untreated NPC patients were examined by CT scan. The prognostic factors ware evaluated by univariate and multivariate analyses on SPSS 8.0 software.Results The actual survival rate, disease free survival rate and local failure free rate were negatively affected by the presence of parapharygneal space involvement ( P =0.011 5, P =0.003 5, P = 0.036 7). The 5 year actual survival rate, disease free survival rate and local failure free rate in patients without tumor invasion to parappharyngeal space was 87.9%, 88.0% and 96.9%, respectively. The survival rate in patients with tumor invasion to prestyloid space was 75.0%, 71.2% and 93.7%, respectively. That in patients with tumor invasion to poststyloid space was 60.5%, 57.7% and 86.8%, respectively. The 5 year distant metastasis free survival rate was 88.1% in patients without poststyloid involvement as compared to 73.8% in those with poststyloid involvement. Conclusion The survival and local tumor control are affected by parapharyngeal space involvement. Distant metastasis is more likely to occur when the tumor growth involves poststyloid space.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2001年第3期244-246,共3页
Chinese Journal of Oncology
关键词
鼻咽肿瘤/放射疗法
预后
咽旁间隙受侵
Nasopharyngeal neoplasms/radiotherapy
Prognosis
Parapharyngeal space involvement
