摘要
目的：对朴实汤剂的剂型改进。方法：通过溶剂选择和正交设计筛选合理的提取工艺，并制订质量控制方法。结果：提取工艺为６倍５０ ％乙醇加热回流２次，每次１．５ｈ。结论：提取工艺合理，质量控制较为全面，奠定了较好的临床前药学研究基础。
OBJECTIVE: To study the pharmaceutics in re- formation of Pushi decoction. METHODS: To establish the qual- ity control methods and optimize the extractive process by or- thogonal design. RESULTS: The optimum extraction condition was that adding six times amount of 50% alcohol as solution, stotally refluxing for 2 times, 1.5 h at each time. The methods, which of determining content of main ingredients and identifica- tions of other three Chinese materia medica by TLC, were in- vestigated. CONCLUSION: The tachnologieal process was suit for preparation of Pushi granules.
出处
《华西药学杂志》
CAS
CSCD
2001年第3期188-190,共3页
West China Journal of Pharmaceutical Sciences
关键词
朴实颗粒剂
制备工艺
质量控制
制剂学
Pushi granules
Extractive process
Quality control methods
