摘要
目的 探讨室内常见气传真菌代谢提取物的免疫抑制作用。方法 监测室内环境中的气传真菌 ,在此基础上 ,以改良的混合淋巴细胞反应实验研究其代谢产物的免疫抑制作用。结果 室内主要气传真菌属中的青霉属、曲霉属在无明显的细胞毒性浓度下 ,可抑制异型小鼠淋巴细胞混合刺激而产生的增生。
Objective To test the non specific cell immunosuppressive effect induced by the extracts of dominant in door airborne fungal cultures Methods On the basis of sampling of indoor air borne fungi,a modified mixed lymphocyte reaction (MLR) assay was used to test the non specific cell immunosuppressive effect induced by fungal cultures extracts Results The extracts of Aspergillus sp and Penicillium sp could inhibit the MLR without causing cytotoxicity Conclusion The result suggested that exposure to fungal culture might become a risk factor to human immune function,especially to respiratory defense system
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2001年第4期201-203,共3页
Journal of Environment and Health
基金
卫生部科技基金资助 (98- 1 - 1 67)
