摘要
为探讨用新标准诊断的糖尿病患者是否存在过度糖化 ,即糖化血红蛋白 (HbA1c)增高 .对 56 8例患者进行口服 75g葡萄糖耐量试验 (OGTT) ,测定空腹血糖 (FPG)及OGTT 2h血糖浓度 ,同时测定空腹HbA1c水平 .结果表明 :FPG正常的患者HbA1c水平 91.0 %正常 ,9.0 %增高 ;在空腹血糖异常 (IFG)组中HbA1c水平正常者占 80 .0 % ,增高者 2 0 .0 % ;按新的空腹标准诊断为糖尿病的患者HbA1c水平 6 8.5%正常 ,31.5%增高 ;按旧的空腹标准诊断为糖尿病 (FPG≥7.8mmol·L- 1)的患者HbA1c水平 11.4 %正常 ,88.6 %增高 .笔者认为单纯FPG在 7.0～ 7.7mmol·L- 1的个体不应诊断为糖尿病 。
To probe into if individuals with diabetes diagnosed by the new FPG concentration criterion would have excessive glycosylation(elevated glycosylated hemoglobin[HbA 1c]levels),the authors measured fasting plasma glucose(FPG)concentration,2 hour glucose concentration by using oral glucose tolerance tests(OGTT),and fasting HbA 1c levels of 568 subjects.The results showed that among subjects with normal FPG concentration,the normal of HbA 1c levels made up 91.0%,and the elevated 9.0%;among individuals with impaired fasting glucose(IFG),the normal of HbA 1c levels made up 80.0%,and the elevated 20.0%;among diabetic patients diagnosed by the FPG criterion only,the normal of HbA 1c levels made up 68.5%,and the elevated 31.5%;in diabetic patients diagnosed by the former FPG criterion,the normal of HbA 1c levels made up 11.4%,and the elevated 88.6%.Thus the authors thought that diabetes should not be diagnosed in those with FPG concentration of 7.0 to 7.7 mmol·L -1 unless excessive glycosylation is evident.
出处
《海南大学学报（自然科学版）》
CAS
2001年第2期166-168,共3页
Natural Science Journal of Hainan University
