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CD44V6、VEGF在胃癌中的表达及其临床意义 被引量:2

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摘要 目的 研究CD44V6、VEGF蛋白在正常胃粘膜、癌前病变以及胃癌的表达和它们与胃癌临床病理关系。方法 应用免疫组化S—P法对三种胃组织标本CD44V6及VEGF的表达情况进行观察。结果 正常胃粘膜无CD44V6、VEGF表达。癌前病变CD44V6、VEGF阳性表达率分别为 9.4%、12 .5 %。胃癌的阳性表达率为 6 4.7%和 5 8.5 % ,随浸润深度加深 ,淋巴结或远处转移、TNM分期上升、CD44V6、VEGF而升高。结论 CD44V 6、VEGF的表达随胃癌的进展而升高 ,据此可作为判定胃癌恶性程度的指标 ;与浸润深度、淋巴结及远处转移、TNM分期呈正相关 ,检测CD44V6。
出处 《临床外科杂志》 2001年第4期242-243,共2页 Journal of Clinical Surgery
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同被引文献58

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