摘要
分析 15 1例甲亢病人治疗前肝功能受损情况。统计肝功能生化指标异常例数和不同甲亢类型、血FT3、FT4 水平及各年龄段肝功能的受损例数。结果显示 :有 96例 (6 3 .5 8% )病人至少有一项指标异常 ,其中 43例 (44 .79% )有二项以上指标异常 ,以ALP异常为主 (5 4.30 % ) ,其次为ALT(35 .10 % ) ,与其他指标差异有显著性 (P <0 .0 1) ,血FT3 和 (或 )FT4 水平越高 ,越易发生肝功能损害 (P <0 .0 1) ,老年更易发生肝功能损害 (P <0 .0 1) ,而不同甲亢类型发生肝功能损害则差异无显著性 (P >0 .0 5 )。提示甲亢病人治疗前发生肝功能损害以ALP、ALT异常为主 ,血FT3 和 (或 )FT4
The diseased condition of hepatic function in 151 patients with hyperthyroidism was retrospectively analyzed. The following items were calculated: the abnormal biochemical indices of hepatic function, different hyperthyroidism classification, blood FT 3 and FT 4 levels and the diseased condition of hepatic function in different ages. Results showed that 96 patients (63.58%) had at least one item of an abnormal index, and 43 of them (44.79%) had more than two items of abnormal indices. The main abnormal index was ALP (54.30%), while the second was ALT (54.30%). The differences of these two indices between others' were statistically different (P<0.01). Also the higher the blood FT 3 and (or) FT 4 levels were the more likely the hepatic function was to be diseased (P<0.001). The elderly men tended to get damaged hepatic function more easily (P<0.01). But in different types of hyperthyroidism, there were no statistical significant differences of injured hepatic function (P>0.05). This study indicates that the chief abnormal hepatic function is ALP and ALT. The higher the blood FT 3 and (or) FT 4 levels in the elderly patients the more likely abnormal liver function could occur.
出处
《右江民族医学院学报》
2001年第4期516-517,共2页
Journal of Youjiang Medical University for Nationalities
