摘要
目的 :探讨部分脾栓塞术 (PSE)治疗肝癌伴门脉高压及脾亢的价值。材料与方法 :12 8例患者白细胞、血小板平均值分别为 2 6× 10 9/L、5 6 8× 10 9/L ,食道胃底静脉曲张 98例 (76 6 % ) ,门静脉癌栓 38例 (2 9 7% ) ,肝动脉 门静脉瘘 2 5例 (19 5 % )。全部患者在肝癌介入治疗的同时行PSE ,其中 32例行 2次以上。结果 :85 9% (110 /12 8)患者术后白细胞及血小板恢复正常 ,2个月复查白细胞、血小板平均值分别为 5 7× 10 9/L、16 9 2× 10 9/L ,6个月复查为 4 8× 10 9/L、110 5×10 9/L ,较术前明显增高 ,门脉高压症状减轻 ,肝功能改善 ,1、2、3年存活率分别为 6 8 1%、38 2 %、2 0 6 %。结论 :肝脾双介入治疗肝癌伴门脉高压、脾亢是一种安全有效的方法 ,伴门静脉癌栓、肝动脉
Purpose: To evaluate the usefulness of partial spleen embolization (PSE) for treatment liver cancer with portal hypertension and hypersplenism. Materials and Methods: The average white blood cell and thrombocyte counts were 2 6×10 9/L and 56 8×10 9/L respectively in 128 patients. Among these cases, 98 cases (76 6%) suffered from esophagogastric vein varication, 38 cases (29 7 9%) with tumor thrombi of portal vein, and 25 cases (19 5%) with hepatic arterio portal shunt. All patients received hepatic arterial chemoinfusion (HAI) and/or chemoembolization (HAE) with PSE, 32 in 128 patients received PSE twice or more. Results: The white blood cell and thrombocyte counts were return to normal in 85 9% (110/128) after received the first PSE. 2 and 6 months after operation, the average white blood cell and thrombocyte counts achieved 5 7×10 9/L and 169 2×10 9/L, 4 8×10 9/L and 110 5×10 9/L respectively. The symptoms of portal hypertension were some relief, and the hepatic functions were improved. The survival rate were 68 1%, 38 2% and 20 6% respectively in follow up for 1, 2, 3year. Conclusions: The hepato splenic interventional therapy is a safe and effective therapeutic method for treatment liver cancer with portal hypertension and hypersplenism. The patients with tumor thrombi of portal vein and/or hepatic arterio portal shunt are also effective by PSE with HAI/HAE.
出处
《中国医学影像学杂志》
CSCD
2001年第4期261-262,265,共3页
Chinese Journal of Medical Imaging
关键词
肝癌
门脉高压
脾亢
部分脾栓塞术
介入疗法
治疗
liver cancer
portal hypertension
hypersplenism
PSE
interventional therapy
