摘要
1目的 探讨血清雌二醇 (Estradiol,E2 )、睾酮 (Testosterone,T)在男性脑梗死患者发病过程中的变化及其临床意义。 2方法 采用放射免疫法 ,动态检测 62例男性脑梗死患者血清 E2 、T浓度 ,分析其与梗死病程、部位、梗死灶大小及病情的关系。 3结果 1男性脑梗死患者急性期血清 E2 值升高 ,T值下降 ,与对照组比较 ,差异均有显著性 (P<0 .0 1) ,恢复期血清 E2 、T值逐渐恢复到接近正常水平 ,与对照组比较 ,差异无显著性。 2急性期皮质下梗死组血清 E2 、T值均低于皮质梗死组 (P<0 .0 5 )。 3急性期梗死灶体积大者血清 E2 值低于梗死灶体积小者 (P<0 .0 5 ) ,而 T值变化不大。 4急性期重型脑梗死患者 E2 、T值均低于轻型患者 (P<0 .0 5 )。 4结论 男性脑梗死患者存在性激素 (E2 、T)失衡现象 ,血清性激素 (E2 、T)值的变化与脑梗死患者的病程、梗死部位。
Objective To investigate the clinical significance and the changes of estradiol (E 2) and testosterone(T) in male patients with cerebral infarction.Methods By RIA test,the levels of serum E 2 and T were dynamic observed in 62 male patients with cerebral infarction.To analyze the relationship between the changes of E 2、T and the religion,size,stage and condition of the infarction.Results ①The serum E 2 concentrations were increased and T were decreased in acute stage of the male cerebral infarction patients,which had remarkable difference from those of the control group(P<0.01).The serum E 2 and T returned to normal level in the convalescent stage,It was no significant diffence. ②During the acute stage of the patients, the levels of serum E 2 and T in patients with subcortex infarction were significantly lower than those of cortex infarction(P<0.05),the levels of serum E 2 in patients with large size infarction were lower than those of small size infarction(P<0.05),However the change of serum T is no significant difference.③During the acute stage of the patients.④The levels of serum E 2 and T in patients with severe cerebral infarction were lower than those of mild cerebral infarction in acute stage(P<0.05). Conclusion The levels of E 2 and T in the male patients with cerebral infarction were disturbance. There is remarkable relationship between the changes of E 2 、T and the religion,size, stage and prognosis of infarction. [
出处
《华北煤炭医学院学报》
2001年第4期397-398,共2页
Journal of North China Coal Medical College
