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2-硝基-4-乙酰胺基苯甲酸的合成 被引量:1

Preparation of 2-nitro-4-acetaminobenzoic acid
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摘要 Nys等报道,2-硝基-4-苯乙酰胺基苯甲酸(2-nitro-4-phenyl acetaminobenzoicacid,简称 PANBA)可以作为分光光度法直接测定青霉素酰化酶活性的底物,但国内尚未见到这方面的报道,为此我们试图合成 PANBA。标题物是合成 PANBA 的中间体。我们以甲苯为原料,经过硝化、选择性还原、保护氨基、氧化而制得,总收率32.4%。
机构地区 河北大学化学系
出处 《化学试剂》 CAS CSCD 北大核心 1991年第6期381-382,共2页 Chemical Reagents
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