摘要
目的 :旨在观察电针心经腧穴“神门”、“少海”对大鼠高血脂症模型血浆内皮素 (ET)、降钙素基因相关肽 (CGRP)含量的影响。方法 :给大鼠饲喂高脂饲料制备高血脂症模型。结果 :动物高血脂症血浆中ET含量明显升高 ,CGRP含量明显下降 ,而电针可使动物血浆ET含量下降 ,CGRP含量升高 ,且神门穴较少海穴效应显著。结论 :电针可调节ET和CGRP向正常水平逆转 ,使组织和血浆中的ET、CGRP水平保持动态平衡 ,从而有利于血管运动平衡 ,使高血脂症所致的缺血、缺氧及代谢障碍得以缓解 ,达到修复或改善血管内皮功能 ,推迟高血症演变过程 。
Objective:The study,selecting spceific points“shenmen” and “shaohai” of hand-shaoyin heart meridian,observed the influence on ET,CGRP on hyperlipidemia in rat.Methods:hyperlipidemia model in rat was set up by feeding with high fatty diet.Results:(1)ET in blood plasma was reduced,and CGRP was increased obviously after EA therapy.(2)The therapeutic effect of EA at “shenmen” on hyperlipidemia was better than at “shaohai”.Conclusion:acupuncture could regulate ET and CGRP returning to normal level.Thus tissular and vascular ET and CGRP could keep dynamic balance,which improved vascular endothelial function and delay the course of atherosclerosis.
出处
《中国中医基础医学杂志》
CAS
CSCD
2001年第5期60-62,共3页
JOURNAL OF BASIC CHINESE MEDICINE
关键词
高脂血症
心经腧穴
内皮素
降钙素基因相关肽
电针
Hyperlipidemia
Points of hand-shaoyin heart meridian
Endothelin (ET)
Calaitonin gene related peptide (CGRP)
Electroacupuncture (EA)
