摘要
110 例伴有呼衰和心衰的慢性肺心病( C P H D) 者随机分为观察组(60 例) 和对照组(50 例) ,对照组采用常规治疗,观察组在常规治疗的基础上加用苄胺唑啉( P H L) 、多巴胺( D A) 及卡托普利( C P) 。通过对两组病人的临床和动脉血气的监测发现:扩血管治疗既可显著提高常规治疗的疗效( P< 005) ,还可通过促进心肺功能的改善,显著升高 Pa O2 ,降低 Pa C O2( P 均< 005) ;未见明显不良反应。
To evaluate the effect of vasodilator therapy on severe cor pulmonale ,the clinical phenom ena andarterial blood gas levels were studied in 110 patients with severe cor pulm onale acco m panied by respiratoryfailure and heart failure . Sixty of the m were treated with phentolamine ,dopa mine and captopril on top ofroutine treatment . The results show ed that vasodilator therapy dram atically raised the therapeutic effect ofroutine treatment ( P < 0 .05) , Pa O2 was increased rem arkably ( P < 0 .05) and Pa C O2 w as reducedmarkedly( P< 0 .05) due to im prove ment of the cardiac and pulm onary function . No significant side effectof vasodilator was observed . These findingsindicate that vasodilator therapy is an effective and safe m ethodfor severe cor pulm onale .
出处
《皖南医学院学报》
CAS
1999年第1期21-22,共2页
Journal of Wannan Medical College
关键词
肺心病
呼吸衰竭
心力衰竭
扩血管治疗
CPHD
Pulm onary heat disease
Respiratory failure
Heart failure
Vasodilator therapy