摘要
目的 :比较 5-单硝酸异山梨醇酯与硝酸异山梨醇酯对冠心病心绞痛的疗效。方法 :对 80例冠心病心绞痛病人随机分为两组 ,分别给予 5-单硝酸异山梨醇酯和硝酸异山梨醇酯治疗。结果 :5-单硝酸异山梨醇酯总有效率为 92 .5% ,硝酸异山梨醇酯为 72 .5% ( P<0 .0 5) ;对心电图的疗效前者为 62 .5% ,后者为 55%( P>0 .0 5)。两组血压、心率变化无显著性差异。结论 :5-单硝酸异山梨醇酯对冠心病心绞痛的疗效优于硝酸异山梨醇酯。
Objective:To compare the efficacy of isosorbide mononitrate and isosorbide dinitrate in patients with angina pectoris.Methods:80 cases were randomly assigned into two groups.Isosorbide mononitrate group (n=40) 60～120 mg/d,isosorbide dinitrate group(n=40) 40～120 mg/d,for 4 weeks.Results:The total effective rate was 92 5% in the isosorbide mononitrate group,and 72 5% in the isosorbide dinitrate group( P <0 05).Conclusion:Isosorbide mononitrate is more effective in the treatment for angina pectoris.
出处
《滨州医学院学报》
2000年第2期117-118,共2页
Journal of Binzhou Medical University
