摘要
[目的]通过临床病理学研究 ,证实直肠癌扩大根治术的合理性 ,从而指导直肠癌的治疗。[方法]通过对进展期直肠癌进行三方向淋巴结清扫获得的标本 ,以常规病理学方法研究淋巴结转移规律 ,并以此规律指导临床进行扩大根治手术 ,统计其治疗效果。[结果]国人进展期直肠癌淋巴转移率为47 % ,上方1、2、3站转移率分别为44 % ,14 %及10% ,侧方第3站转移率为9 %。直肠癌淋巴转移与肿瘤浸润周径、深度及病理学类型有关。扩大根治术后的5年及10年生存率为68 %及47 % ,高于一般根治术的45 %及39 8 %。[结论]直肠癌扩大根治术清除了可能发生转移的所有淋巴结 ,减少了转移淋巴结残留 ,可明显提高生存率。
To confirm the rationality of extended radical resection for the rectal cancer with clinicopathological methods.The node specimens were obtained from lymphanectomy of 3 fields in advanced rectal cancer.The rule of lymphatic metastasis was studied by routine pathological method.The therapeutic effect of the extended radical resection based on the metastatic rule was investigated.The rate of lymphatic metastasis in advanced rectal cancer in Chinese was 47%.The metastatic rates of the 1st,2nd and 3rd station in the superior field were 44%,14% and 10% respectively;and the lateral 3rd station,9%.The lymphometastasis in the rectal cancer related with perimeter and depth of invasion,and the pathological type.The rate of 5 year survival and 10 year survival were 68% and 47%respectively,which were much higher than that in routine radical resection.[Conclusion]The extended radical resection cleans the possible metastatic nodes in rectal cancer,and may improve survival markedly.
出处
《肿瘤学杂志》
CAS
2001年第1期28-30,共3页
Journal of Chinese Oncology
关键词
直肠肿瘤
淋巴转移
临床病理学
生存率
外科手术
rectal neoplasms
lymphatic metastasis
clinicopathology
survival rate
surgery
