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高眼压症与角膜厚度 被引量:13

Ocular hypertension and corneal thickness
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摘要 目的 :评价角膜厚度在高眼压症眼压测量中的作用影响。方法 :选取 34例 (6 8眼 )高眼压症患者 (眼压≥ 2 1mm Hg,≤ 35 mm Hg,正常视野 ,正常视神经乳头 ,无角膜水肿等病变 )均为复旦大学医学院眼耳鼻喉科医院眼科门诊患者 ,年龄 6~ 6 5岁 (19.70±13.5 2 ) ,平均 2 0岁 ,男性 18例 ,女性 2 0例。由专人应用 Goldmann压平眼压计测量眼压 ,由专人应用 Sonoscan Model40 0 0 APA型超声测量中央角膜厚度。结果 :34例 6 8眼眼压范围 2 1~ 35 mm Hg,平均 2 4.892± 2 .885 mm Hg;中央角膜厚度 0 .5 2 3~0 .6 37mm,平均 0 .5 88± 0 .0 2 8mm。应用 SPSS软件包经 K—S检验二组数据 P值分别为 0 .30 6 1、 0 .842 2均呈正态分布 ,应用Pearson s相关统计法 ,二组数据呈正相关 ,相关系数为 0 .2 82 4,P=0 .0 2 (P<0 .0 5 )。根据本组病例可得出一相关方程式 :Y(眼压 ) =42 .40 1X(中央角膜厚度 )。即每 0 .0 2 36 mm的中央角膜厚度变化可有 1mm Hg的压平眼压值改变。结论 :中央角膜厚度与眼压测量值呈正相关 ,高眼压症患者眼压值的升高与中央角膜厚度的变化有关 ,揭示高眼压症患者的真正眼压可能是正常的 ,只是由于中央角膜厚度的变异使眼压测量值偏高。 Objective:To evaluate the effect of central corneal thickness (CCT) on applanation tonometry of ocular hypertension (OHT). Methods: Thirty-four cases(68 eyes) with OHT (21mmHg≤intraocular pressure[IOP]( 35mmHg) were all out-patients. Ages were from 6 to 65 years old (19.70(3.52). Men were 18 cases, women 20 cases. IOP was measured by Goldman applanation tonometer. CCT was determined with A type ultrasonography (Sonoscan Model 4000AP). Results: The mean ( SD of CCT in patients with OHT was 0.588 ( 0.28mm, the IOP was 24.892(885mmHg. According to the K-S test by SPSS soft, P values in the two groups were 0.3061 and 0.8422, respectively and both in normal distribution. Application of person's correlation statistic analysis showed that there was a positive correlation between the two groups, correlation coefficient was 0.2824, p = 0.02 (p<0.05). Correlation equation, Y=42.401X, was attained in term of the data. It meant that applanation tonometry is over/under estimated by approximately l mmHg for every 0.0236mm in CCT. Conclusion: The IOP is positively correlated with CCT. Variation of CCT results in elevation of IOP of patients with OHT, but the real IOP may be normal.
作者 肖明 孙兴怀
出处 《中国实用眼科杂志》 CSCD 北大核心 2001年第4期276-278,共3页 Chinese Journal of Practical Ophthalmology
关键词 高眼压症 角膜厚度 测量 Ocular hypertension, Cornea
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  • 1王兴淼.角膜区域划分及投影胶片研制的探讨[J]实用眼科杂志,1987(06).

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